J Korean Med Sci. 1992 Dec;7(4):369-372. English.
Published online May 27, 2009.
https://doi.org/10.3346/jkms.1992.7.4.369
Published online May 27, 2009.
https://doi.org/10.3346/jkms.1992.7.4.369
Copyright © 1992 The Korean Academy of Medical Sciences
Case Report
Primary choriocarcinoma of the urinary bladder: a case report
Jeong Hee Cho,
Eun Sil Yu,
Kwang Hoon Kim
and In Chul Lee
Abstract
We report a primary choriocarcinoma of the urinary bladder in a 63-year-old man who presented with painless hematuria. He was diagnosed as having an invasive carcinoma and underwent a total cystectomy. The tumor was diffusely hemorrhagic and occupied the dome of the bladder. Histologically, it consisted of cyto-and syncytiotrophoblasts with extensive hemorrhage. No coexisting transitional cell carcinoma component was present. By immunohistochemistry, the tumor expressed beta-hCG and low-molecular weight cytokeratin intensely while it was negative for CEA or EMA. The post-cystectomy serum beta-hCG was 237mlU/ml, and decreased later. The pertinent literature is reviewed and diagnostic criteria are discussed.
Keywords
Choriocarcinoma; Urinary bladder; Immunohistochemical study
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