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Study found that higher doses of intensity-modulated radiotherapy (IMRT), up to 81 Gy, can improve biochemical survival for patients with localised prostate cancer. Data also suggest that toxicity can be reduced by increasing conformality of treatment, particularly with regard to gastrointestinal (GI) toxicity, which can be more easily achieved with IMRT than three-dimensional conformal radiotherapy (3DCRT). Whether differences in GI toxicity between IMRT and 3DCRT are sufficient for IMRT to be cost-effective is uncertain, depending on the difference in incidence of GI toxicity, its duration and the cost difference between IMRT and 3DCRT
School of Health and Related Research (ScHARR), The University of Sheffield, Sheffield, UK
* Corresponding author Email: s.hummel@sheffield.ac.uk
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