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Consensus Statement

Consensus statement from the International Radiosurgery Oncology Consortium for Kidney for primary renal cell carcinoma

    Shankar Siva

    *Author for correspondence:

    E-mail Address: shankar.siva@petermac.org

    Division of Radiation Oncology & Cancer Imaging, Peter MacCallum Cancer Center, East Melbourne, Australia

    ,
    Rodney J Ellis

    University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, OH, USA

    ,
    Lee Ponsky

    University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, OH, USA

    ,
    Bin S Teh

    Houston Methodist Hospital, Weil Cornell Medical College, Houston, TX, USA

    ,
    Anand Mahadevan

    Beth Israel Deaconess Medical Center, Boston, MA, USA

    ,
    Alexander Muacevic

    University of Munich Hospitals, Munich, Germany

    ,
    Michael Staehler

    University of Munich Hospitals, Munich, Germany

    ,
    Hiroshi Onishi

    Department of Radiology, University of Yamanashi, Yamanashi, Japan

    ,
    Peter Wersall

    Karolinska University Hospital/Karolinska Institute, Stockholm, Sweden

    ,
    Takuma Nomiya

    National Institute of Radiological Sciences, Chiba, Japan

    &
    Simon S Lo

    University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, OH, USA

    Published Online:https://doi.org/10.2217/fon.16.2

    Aim: To provide a multi-institutional consensus document for stereotactic body radiotherapy of primary renal cell carcinoma. Materials & methods: Eight international institutions completed a 65-item survey covering patient selection, planning/treatment aspects and response evaluation. Results: All centers treat patients with pre-existing hypertension and solitary kidneys. Five institutions apply size constraints of 5–8 cm. The total planning target volume expansion is 3–10 mm. All institutions perform pretreatment imaging verification, while seven institutions perform some form of intrafractional monitoring. Number of fractions used are 1–12 to a total dose of 25 Gy–80 GyE. Imaging follow-up for local tumor response includes computed tomography (n = 8), PET-computed tomography (n = 1) and MRI (n = 5). Follow-up frequency is 3–6 months for the first 2 years and 3–12 months for subsequent 3 years. Conclusion: Key methods for safe implementation and practice for stereotactic body radiotherapy kidney have been identified and may aid standardization of treatment delivery.

    Papers of special note have been highlighted as: • of interest; •• of considerable interest

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