Abstract
Background: Cardiovascular disease (CVD) as a result of macrovascular changes is the leading cause of mortality in patients with type 1 diabetes (T1DM). While CVD complications are seen predominantly in adulthood, the atherosclerotic process begins in childhood and is accelerated in patients with T1DM. This review focuses on the epidemiology of traditional CVD risk factors in adolescents with T1DM, its association with markers of CVD and an overview of studies looking into each individual risk factor.
Conclusion: The risk factors that are reviewed here are hypertension, dyslipidemia, smoking, obesity, lack of exercise, hyperglycemia and diabetic nephropathy. We highlight the importance of early identification, and interventions, which include optimizing glycemic control, pharmacotherapy, regular physical activity and dietary changes.
Keywords: Cardiovascular risk factors, type 1 diabetes, adolescents, cardiovascular disease, epidemiology, obesity.
Current Diabetes Reviews
Title:Traditional Cardiovascular Risk Factors in Adolescents with Type 1 Diabetes Mellitus
Volume: 13 Issue: 6
Author(s): Kim Donaghue*Sze Lyn Jeanne Wong
Affiliation:
- University of Sydney and the Children's Hospital at Westmead, Sydney,Australia
Keywords: Cardiovascular risk factors, type 1 diabetes, adolescents, cardiovascular disease, epidemiology, obesity.
Abstract: Background: Cardiovascular disease (CVD) as a result of macrovascular changes is the leading cause of mortality in patients with type 1 diabetes (T1DM). While CVD complications are seen predominantly in adulthood, the atherosclerotic process begins in childhood and is accelerated in patients with T1DM. This review focuses on the epidemiology of traditional CVD risk factors in adolescents with T1DM, its association with markers of CVD and an overview of studies looking into each individual risk factor.
Conclusion: The risk factors that are reviewed here are hypertension, dyslipidemia, smoking, obesity, lack of exercise, hyperglycemia and diabetic nephropathy. We highlight the importance of early identification, and interventions, which include optimizing glycemic control, pharmacotherapy, regular physical activity and dietary changes.
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Cite this article as:
Donaghue Kim *, Jeanne Wong Lyn Sze , Traditional Cardiovascular Risk Factors in Adolescents with Type 1 Diabetes Mellitus, Current Diabetes Reviews 2017; 13 (6) . https://dx.doi.org/10.2174/1573399813666170124095113
DOI https://dx.doi.org/10.2174/1573399813666170124095113 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
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