Abstract
Depression is a severe medical illness that can interfere with an individuals self-care behaviors. Depression is prevalent [1], burdensome [2], treatable [3], and costly [4]. Recognizing depression in diabetic individuals is critical because depression may play a role in worse control of diabetes and worse diabetes outcomes [5-10]. Depression also appears to increase the costs associated with treating diabetes [11]. A number of clinical trials have recently focused on whether treatment of depression can lead to improved diabetes outcomes [12-15]. In this review, we examine the present state of knowledge on the interaction of depression and diabetes, discuss the epidemiologic and physiologic evidence for the co-occurrence of these conditions, and describe the ways in which diabetes control is worsened by depression, how depression interferes with diabetes care, and how depression acts to increase costs in diabetics. We focus specifically on interventions to treat depression in patients with diabetes and suggest areas of future research and practice with respect to improving care and outcomes those suffering in the intersection of these diseases.
Keywords: heart diseases, serotonin re-uptake inhibitors, non-diabetic control group, depression
Current Diabetes Reviews
Title: The Interaction of Depression and Diabetes: A Review
Volume: 3 Issue: 4
Author(s): Paul A. Pirraglia and Smita Gupta
Affiliation:
Keywords: heart diseases, serotonin re-uptake inhibitors, non-diabetic control group, depression
Abstract: Depression is a severe medical illness that can interfere with an individuals self-care behaviors. Depression is prevalent [1], burdensome [2], treatable [3], and costly [4]. Recognizing depression in diabetic individuals is critical because depression may play a role in worse control of diabetes and worse diabetes outcomes [5-10]. Depression also appears to increase the costs associated with treating diabetes [11]. A number of clinical trials have recently focused on whether treatment of depression can lead to improved diabetes outcomes [12-15]. In this review, we examine the present state of knowledge on the interaction of depression and diabetes, discuss the epidemiologic and physiologic evidence for the co-occurrence of these conditions, and describe the ways in which diabetes control is worsened by depression, how depression interferes with diabetes care, and how depression acts to increase costs in diabetics. We focus specifically on interventions to treat depression in patients with diabetes and suggest areas of future research and practice with respect to improving care and outcomes those suffering in the intersection of these diseases.
Export Options
About this article
Cite this article as:
Pirraglia A. Paul and Gupta Smita, The Interaction of Depression and Diabetes: A Review, Current Diabetes Reviews 2007; 3 (4) . https://dx.doi.org/10.2174/1573399810703040249
DOI https://dx.doi.org/10.2174/1573399810703040249 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Mannose Binding Lectin: A Potential Biomarker for Many Human Diseases
Current Medicinal Chemistry Targeting the MCP-1/CCR2 System in Diabetic Kidney Disease
Current Vascular Pharmacology Curcumin: Structure-Activity Relationship Towards its Role as a Versatile Multi-Targeted Therapeutics
Mini-Reviews in Organic Chemistry High-Throughput Proteomics: A New Tool for Quality and Safety in Fishery Products
Current Protein & Peptide Science Perspectives on New Synthetic Curcumin Analogs and their Potential Anticancer Properties
Current Pharmaceutical Design Approaches to Target Profiling of Natural Products
Current Medicinal Chemistry Editorial (Thematic Issue: New Therapeutic Targets in Clinical Medicine)
Current Pharmaceutical Design The Promise of Cholesteryl Ester Transfer Protein (CETP) Inhibition in the Treatment of Cardiovascular Disease
Current Pharmaceutical Design Bioactive Milk Lipids
Current Nutrition & Food Science Cardiac Telocytes
Current Stem Cell Research & Therapy Chemistry and Applications of 4-Hydroxyquinolin-2-one and Quinoline-2,4-dionebased Compounds
Current Organic Chemistry Hypertension in Older Patients
Current Hypertension Reviews Flavonoids: Prospective Drug Candidates
Mini-Reviews in Medicinal Chemistry Protocatechuic Acid and Human Disease Prevention: Biological Activities and Molecular Mechanisms
Current Medicinal Chemistry Vascular Effects of Estrogenic Menopausal Hormone Therapy
Reviews on Recent Clinical Trials Coronary CT and the Coronary Calcium Score, the Future of ED Risk Stratification?
Current Cardiology Reviews Dealing with the Substance Abuse Epidemic and Infective Endocarditis:Clinical, Immunologic and Pathogenetic Aspects
Current Vascular Pharmacology Anti-Inflammatory Properties of Drugs from saffron crocus
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Potential Application of Dietary Polyphenols from Red Wine to Attaining Healthy Ageing
Current Topics in Medicinal Chemistry Tissue Distribution and Pharmacodynamics: A Complicated Relationship
Current Drug Metabolism