Abstract
The aim of this review is to update current knownledge on the betulinic, ursolic and echinocystic acids and their natural and semisynthetic analogs, focussing on their cytotoxic and anti-HIV activities. Then, the last results of the authors team on unusual semisynthetic derivatives of these triterpenoids will be presented in order to establish structure / activity relationships.
Keywords: betulinic, ursolic, echinocystic acid, antitumor, anti-hiv agents, anti-hiv activities
Mini-Reviews in Medicinal Chemistry
Title: A Review of Natural and Modified Betulinic, Ursolic and Echinocystic Acid Derivatives as Potential Antitumor and Anti-HIV Agents
Volume: 3 Issue: 6
Author(s): I. Baglin, A.- C. Mitaine-Offer, M. Nour, K. Tan, C. Cave and M.- A. Lacaille-Dubois
Affiliation:
Keywords: betulinic, ursolic, echinocystic acid, antitumor, anti-hiv agents, anti-hiv activities
Abstract: The aim of this review is to update current knownledge on the betulinic, ursolic and echinocystic acids and their natural and semisynthetic analogs, focussing on their cytotoxic and anti-HIV activities. Then, the last results of the authors team on unusual semisynthetic derivatives of these triterpenoids will be presented in order to establish structure / activity relationships.
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Cite this article as:
Baglin I., Mitaine-Offer C. A.-, Nour M., Tan K., Cave C. and Lacaille-Dubois A. M.-, A Review of Natural and Modified Betulinic, Ursolic and Echinocystic Acid Derivatives as Potential Antitumor and Anti-HIV Agents, Mini-Reviews in Medicinal Chemistry 2003; 3 (6) . https://dx.doi.org/10.2174/1389557033487917
DOI https://dx.doi.org/10.2174/1389557033487917 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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