Abstract
The number of people with diabetes is expected to rise from the current estimated 150 million to 220 million in 2010 and 300 million in 2025, and 90% is Type 2 diabetes or non-insulin dependant diabetes mellitus (NIDDM). Voglibose, one of the most important α-glucosidase inhibitors, delays the digestion and absorption of carbohydrates, thereby inhibiting postprandial hyperglycemia and hyperinsulinemia, and is the aid in the treatment of diabetes. In this paper, properties and the preparation of voglibose are reviewed.
Keywords: Voglibose, Glucosidase inhibitor, Preparation, NIDDM
Current Medicinal Chemistry
Title: Voglibose (Basen®, AO-128), One of the Most Important α-Glucosidase Inhibitors
Volume: 13 Issue: 1
Author(s): Xiaolong Chen, Yuguo Zheng and Yinchu Shen
Affiliation:
Keywords: Voglibose, Glucosidase inhibitor, Preparation, NIDDM
Abstract: The number of people with diabetes is expected to rise from the current estimated 150 million to 220 million in 2010 and 300 million in 2025, and 90% is Type 2 diabetes or non-insulin dependant diabetes mellitus (NIDDM). Voglibose, one of the most important α-glucosidase inhibitors, delays the digestion and absorption of carbohydrates, thereby inhibiting postprandial hyperglycemia and hyperinsulinemia, and is the aid in the treatment of diabetes. In this paper, properties and the preparation of voglibose are reviewed.
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Cite this article as:
Chen Xiaolong, Zheng Yuguo and Shen Yinchu, Voglibose (Basen®, AO-128), One of the Most Important α-Glucosidase Inhibitors, Current Medicinal Chemistry 2006; 13 (1) . https://dx.doi.org/10.2174/092986706789803035
DOI https://dx.doi.org/10.2174/092986706789803035 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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