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Exercise, Muscle Damage and Fatigue

  • Issues in Fatigue in Sport and Exercise
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Summary

Fatigue as a functional sign and muscle damage as a structural sign can be observed after prolonged exercise like marathon running or after strenuous exercise, especially with the involvement of eccentric contractions. For fatigue due to prolonged exercise, hypoxic conditions and the formation of free oxygen radicals seem to be of aetiological importance, resulting in an elevated lysosomal activity. Eccentric exercise of high intensity rather results in a mechanical stress to the fibres. Although these different mechanisms can be discerned experimentally, both result in similar impairments of muscle function. A good training status may attenuate the clinical signs of fatigue and muscle damage. The symptoms and events occurring during delayed onset of muscle soreness (DOMS) can be explained by a cascade of events following structural damage to muscle proteins.

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Authors and Affiliations

  1. Institute for Experimental Morphology, German Sports University, P.O. Box 450327, D-5000, Cologne 41, Federal Republic of Germany

    H.-J. Appell

  2. Department of Sport Biology, University of Porto, Portugal

    J. M. C. Soares & J. A. R. Duarte

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  1. H.-J. Appell
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  2. J. M. C. Soares
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  3. J. A. R. Duarte
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Appell, HJ., Soares, J.M.C. & Duarte, J.A.R. Exercise, Muscle Damage and Fatigue. Sports Medicine 13, 108–115 (1992). https://doi.org/10.2165/00007256-199213020-00006

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  • DOI: https://doi.org/10.2165/00007256-199213020-00006

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