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The Effects of Exercise on Coronary Heart Disease Risk Factors in Children

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Summary

Coronary heart disease (CHD) is now recognised as a paediatric problem despite the fact that clinical symptoms of this disease do not become apparent until much later in life.

Epidemiological studies of risk factors in children have now been conducted. These studies suggest that the risk factors for cardiovascular disease in adults, which include a family history of heart disease, elevated blood lipids (serum cholesterol and triglycerides), obesity, hypertension, smoking, diabetes mellitus and inadequate physical activity, can be identified in children. Several investigators have reported the existence of one or more risk factors in more than 50% of the children they have examined. It is now clear that we can detect most children who are potentially at risk for CHD.

The notion of ‘tracking’ some of the most common CHD risk factors in children has been used in several studies. Results from this type of research indicate that children who are at the extreme end of the distribution and have high levels of blood pressure, adverse lipid levels and are obese will continue to exhibit these coronary risk factors as they grow. The research completed at present does not answer the question of whether children who exhibit a coronary-prone risk factor profile will exhibit this same profile at an age when one is most likely to develop the clinical manifestations of CHD. It does make sense, however, to identify those children who may be at risk for developing premature CHD and to initiate safe interventions such as behaviour modification, changes in diet and increases in physical activity. These have all been shown to alter risk factors which are associated with increased relative risk of CHD in adults. It should be noted that in adults regular aerobic exercise often may alter all risk factors for CHD, including hypertension and diabetes. Whether regular aerobic exercise will induce similar changes in children is not fully understood.

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References

  • Abraham S, Nordsieck M. Relationship of excess weight in children and adults. Public Health Reports 75: 263–273, 1960

    Article  PubMed  CAS  Google Scholar 

  • American College of Sports Medicine. Position statement on the recommended quantity and quality of exercise for developing and maintaining fitness in healthy adults. Medicine and Science in Sport and Exercise 10: vii–x, 1978

    Google Scholar 

  • Adner MM, Castelli WP. Elevated high density lipoprotein levels in marathon runners. Journal of the American Medical Association 343: 534–546, 1980

    Article  Google Scholar 

  • American Health Foundation. Conference on the health effects of blood lipids: optimal distributions for populations. Preventive Medicine 8: 612–678, 1979

    Article  Google Scholar 

  • American Heart Association. Heart Book: A guide to and treatment of cardiovascular disease, E.P. Dutton, New York, 1980

    Google Scholar 

  • American Heart Association. Heart facts, American Heart Association, Dallas, 1982

    Google Scholar 

  • Albert Z. Die Veranderungen der Aorta bei Kindern and ihr Verhaltnis zur Atherosklerose. Virchov’s Archiv für Pathologische Anatomie und Physiologie 303: 265–279, 1939

    Google Scholar 

  • Aristimuno G, Foster T, Voors A, Srinivasan S, Berenson G. Influence of persistent obesity in children on cardiovascular risk factors: the Bogalusa heart study. Circulation 69: 895–904 1984

    Article  PubMed  CAS  Google Scholar 

  • Åstrand PO, Engstrom L, Eriksson B, Karlberg P, Nylander I, et al. Girl swimmers. Acta Paediatrica Scandinavica 147 (Suppl.): 5–75, 1963

    Google Scholar 

  • Bar-Or O, Zwiren LD. Physiological effects of increased frequency of physical education classes and of endurance conditioning on 9 to 10 year old girls and boys. In Bar-Or (Ed.) Pediatric work physiology: Proceedings 4th International Symposium, pp. 183–198, Wingate Institute, Israel, 1973

  • Becker DM, Vaccaro P. Anaerobic threshold alterations caused by endurance training in young children. Journal of Sports Medicine and Physical Fitness 23: 445–449, 1983

    PubMed  CAS  Google Scholar 

  • Bell RD, Macek M, Rutenfranz J, Saris WHM. Health indicators and risk factors of cardiovascular diseases during childhood and adolescence. In Rutenfrantz et al. (Eds) Children and exercise XII, pp. 19–27, Human Kinetics Publishers, Champaign, 1986

    Google Scholar 

  • Berenson GS, Voors AW, Webber LS, Frerichs RR. Blood pressure in children and its interpretation: task force report. Pediatrics 61: 333, 1978

    PubMed  CAS  Google Scholar 

  • Berenson GS. Cardiovascular risk factors in children. Oxford University Press, Oxford, 1980a

    Google Scholar 

  • Berenson GS, Srinivasan SR, Webber LS. Prognostic significance of lipid profiles in children. In Lauer & Shekella (Eds) Childhood prevention of atherosclerosis and hypertension, pp. 75–86, Raven Press, New York, 1980b

    Google Scholar 

  • Boulton J. Nutrition in childhood and its relationship to early somatic growth, body fat, blood pressure, and physical fitness. Acta Pediatrica Scandinavica 284 (Suppl.): 1–85, 1981

    CAS  Google Scholar 

  • Boyer JL, Kasch FW. Exercise therapy in hypertensive men. Journal of the American Medical Association 211: 1668–1671, 1970

    Article  PubMed  CAS  Google Scholar 

  • Brown CH, Harrower JR, Deeter MS. The effects of cross-country running on preadolescent girls. Medicine and Science in Sports 4: 1–5, 1972

    PubMed  CAS  Google Scholar 

  • Brownell KD, Kaye FS. A school-based behavior modification, nutrition education, and physical activity program for obese children. American Journal of Clinical Nutrition 35: 277–283, 1982

    PubMed  CAS  Google Scholar 

  • Brownell K. The psychology and physiology of obesity: implications for screening and treatment. Journal of the American Dietetic Association 84: 447–450, 1984

    Google Scholar 

  • Brunner D, Manelis G, Modan M, Levin S. Physical activity at work and the incidence of myocardial infarction angina pectoris and death due to ischemic heart disease. Journal of Chronic Diseases 27: 217–233, 1974

    Article  PubMed  CAS  Google Scholar 

  • Bryant JG, Garett HL, Dean MS. Coronary heart disease: the beneficial effects of exercise to children. Journal of the Louisiana State Medical Society 136: 15–17, 1984

    PubMed  CAS  Google Scholar 

  • Campaigne BN, Landt MJ, Mellies MD, James FW, Glueck CJ, et al. The effects of physical training on blood lipid profiles in adolescents with insulin dependent diabetes mellitus. Physician and Sportsmedicine 13: 83–89, 1985

    Google Scholar 

  • Castelli WP, Doyle JT, Gordon T. HDL cholesterol and other lipids in coronary heart disease: the cooperative hypoprotein phenotyping study. Circulation 55: 767–772, 1977

    Article  PubMed  CAS  Google Scholar 

  • Choquette G, Ferguson RJ. Blood pressure reduction in ‘borderline’ hypertensives following physical training. Canadian Medical Association Journal 105: 699–703, 1973

    Google Scholar 

  • Clarke WR, Schrott HG, Leaverton PE, Connor WE, Lauer RM. Tracking of blood lipids and blood pressures in school age children: the Muscatine study. Circulation 58: 626–634, 1978

    Article  PubMed  CAS  Google Scholar 

  • Committee on Nutrition of the Mother and Preschool Child. Fetal and infant nutrition and susceptibility to obesity. American Journal of Clinical Nutrition 31: 2026–2030, 1978

    Google Scholar 

  • Connor WE, Cerqueira MR, Rodney MS, Connor RW, Wallace RB, et al. The plasma lipid, lipoproteins, and diet of the Tarahumara Indians of Mexico. American Journal of Clinical Nutrition 31: 1131–1142, 1978

    PubMed  CAS  Google Scholar 

  • Costello C, Disney G, Dodson W, Bush M. Longitudinal study of the incidence and persistence of obesity in girls from ages 9 to 16 years. Federation Proceedings 42: 535, 1983

    Google Scholar 

  • Craddock D. Obesity and its management, Churchill Livingston, New York, 1978

    Google Scholar 

  • Cresanta TL, Webber LS, Srinivasan SR, Berenson GS. Tracking of lipoprotein cholesterol in children over a six year period. CVD Epidemiology Newsletter 33: 41, 1983

    Google Scholar 

  • Dahl-Jorgenson K, Meen HD, Hanssen KF, Aagenaes O. The effect of exercise on diabetic control and hemoglobin A1 (HbA1) in children. Acta Paediatrica Scandinavica 283 (Suppl.): 53–56, 1980

    Article  Google Scholar 

  • Doyard P, Chaussain J, Job J. Adipose tissue cellularity and hormonal data in obese children. In Cacciari et al. (Eds.) Obesity in childhood, Academic Press, London, 1978

    Google Scholar 

  • Durant RH, Linder CW, Harkness JW, Gray RG. The relationship between physical activity and serum lipids and lipoproteins in black children and adolescents. Journal of Adolescent Health Care 4: 55–60, 1983

    Article  PubMed  CAS  Google Scholar 

  • Dwyer T, Coonan WE, Leitch DR, Hetzel BS, Baghurst RA. An investigation of the effects of daily physical activity on the health of primary school students in South Australia. International Journal of Epidemiology 12: 308–313, 1983

    Article  PubMed  CAS  Google Scholar 

  • Ekblom B. Effect of physical training in adolescent boys. Journal of Applied Physiology 27: 350–355, 1969

    PubMed  CAS  Google Scholar 

  • Enos WF, Beyer JC, Holmes RH. Pathogenesis of coronary disease in American soldiers killed in Korea. Journal of the American Medical Association 152: 1090–1093, 1953

    Article  PubMed  CAS  Google Scholar 

  • Eriksson BO, Koch G. Effect of physical training on hemodynamic response during submaximal and maximal exercise. Acta Physiologica Scandinavica 87: 27–39, 1973

    Article  PubMed  CAS  Google Scholar 

  • Errebo-Knudsen EO. Diabetes mellitus and exercise: a physiopathological study of muscular work in patients with diabetes mellitus. Reports of the Steno Memorial Hospital 3: 1–148, 1948

    Google Scholar 

  • Feinleib M, Kannel WB, Garrison RJ, McNamara P, Castelli WP. Relation of parental history of coronary heart disease to risk factors in young adults. Circulation 54: 52, 1976

    Google Scholar 

  • Fisher HG, Brown M. The effects of diet and exercise on selected coronary risk factors in children. Medicine and Science in Sports and Exercise 14: 171, 1982

    Article  Google Scholar 

  • Frank GC, Farris RP, Ditmarsen P, Voors AW, Berenson GS. An approach to primary prevention treatment for children with high blood pressure in a total community. Journal of the American College of Nutrition 1: 357–374, 1982

    PubMed  CAS  Google Scholar 

  • Freidman M, Rosenman RH. Type A behavior and your heart. Fawcett Publications, Greenwich, 1974

    Google Scholar 

  • Garrett HL, Pangle RW, Mann GV. Physical conditioning and coronary risk factors. Journal of Chronic Diseases 19: 899–908, 1966

    Article  PubMed  CAS  Google Scholar 

  • Gilliam TB, Katch VL, Thorland WG, Weltman AW. Prevalence of coronary heart disease risk factors in active children 7 to 12 years of age. Medicine and Science in Sports 9: 21–25, 1977

    PubMed  CAS  Google Scholar 

  • Gilliam TB, Burke MA. Effects of exercise on serum lipids and lipoproteins in girls, ages 8 to 10 years. Artery 4: 203–213, 1978

    CAS  Google Scholar 

  • Gilliam TB, MacConnie SE. Coronary heart disease risk in children and their physical activity patterns. In Boileau (Ed.) Advances in pediatric sport sciences, pp. 171–187, Human Kinetics Publishers, Illinois, 1984

    Google Scholar 

  • Glueck CJ. Detection of risk factors for coronary artery disease in children. Semmel Weis revisited? Pediatrics 66: 834, 1980

    CAS  Google Scholar 

  • Glueck CJ, Fallat RW, Tsang R, Buncher CR. Hyperlipidemia in progeny of parents with myocardial infarction before age 50. American Journal of Diseases of Children 127: 70–75, 1974

    PubMed  CAS  Google Scholar 

  • Gunnarson R, Walberg-Henricksson H, Henricksson J, Ostman J, Wahren J. Exercise and physical training in type I diabetes. In Bostrom & Ljungstedt (Eds) Recent trends in diabetes, Almqvist & Wiskell International, Stockholm, 1982

    Google Scholar 

  • Hagberg JM, Goldring D, Ehsani AA, Heath GW, Hernaude A, et al. Effect of exercise training on the blood pressure and hemodynamic features of hypertensive adolescents. American Journal of Cardiology 52: 763–768, 1983

    Article  PubMed  CAS  Google Scholar 

  • Heldenberg D, Tamir I, Levtow O, Burstein Y, Werbin B. Lipoprotein measurements a necessity for precise assessment of risk in children from high-risk families. Archives of Disease in Childhood 54: 695–698, 1979

    Article  PubMed  CAS  Google Scholar 

  • Holtzman NA. Hyperlipidemia screening: a search for Heffalumps? Pediatrics 64: 270–271, 1979

    PubMed  CAS  Google Scholar 

  • Hueneman R, Hampton M, Behnke H, Schapiro L, Mitchell B. Teenage nutrition and physique, C.C. Thomas, Springfield, 1974

    Google Scholar 

  • Ibsen KK, Lous P, Anderson GE. Coronary heart risk factors in 177 children and young adults whose fathers died from ischemic heart diseases before age 45. Acta Pediatrica Scandinavica 71: 609–613, 1982

    Article  CAS  Google Scholar 

  • Ishiko T, Ikeda N, Enomoto Y. Obese children in Japan. Research Journal of Physical Education 12: 168–174, 1968

    Google Scholar 

  • Johnson ML, Burke BS, Mayer J. Relative importance of inactivity and overeating in the energy balance of obese high school girls. American Journal of Clinical Nutrition 4: 37–44, 1956

    PubMed  CAS  Google Scholar 

  • Johnson WP, Grover JA. Hemodynamics and metabolic effects of physical training in four patients with essential hypertension. Canadian Medical Association Journal 96: 842–846, 1967

    PubMed  CAS  Google Scholar 

  • Kagan AR. Atherosclerosis and myocardial disease in relation to physical activity of occupation. Bulletin World Health Organization 53: 615–622, 1976

    CAS  Google Scholar 

  • Kannel WB. Some lessons in cardiovascular epidemiology from Framingham. American Journal of Cardiology 37: 269–282, 1976

    Article  PubMed  CAS  Google Scholar 

  • Kannel WB. Meaning of the downward trend in cardiovascular morbidity and mortality. Journal of the American Medical Association 247: 877–880, 1982

    Article  PubMed  CAS  Google Scholar 

  • Kannel WB, Castelli WP, Gordon T, McNamara PM. Serum lipoprotein cholesterol and risk of coronary heart disease: the Framingham Study. Annals of Internal Medicine 74: 1–12, 1971

    PubMed  CAS  Google Scholar 

  • Kannel WB, Dawber TR. Atherosclerosis as a pediatric problem. Journal of Pediatrics 80: 544–554, 1972

    Article  PubMed  CAS  Google Scholar 

  • Kannel WB, McGee DL. Diabetes and cardiovascular risk factors: the Framingham Study. Circulation 59: 8–13, 1979

    Article  PubMed  CAS  Google Scholar 

  • Kellet DW, Willan PLT, Bagnall KJ. A study of potential olympic swimmers. Part 2. Changes due to three months of intensive training. British Journal of Sports Medicine 12: 87–92, 1978

    Article  Google Scholar 

  • Kelly P, Sullivan D, Bartsch M, Gracey M, Ridout S. Evolution of obesity in young people in Busselton, Western Australia. Medical Journal of Australia 141: 97–99, 1984

    PubMed  CAS  Google Scholar 

  • Keys A. Coronary heart disease–the global picture. Atherosclerosis 22: 149–192, 1975

    Article  PubMed  CAS  Google Scholar 

  • Klotz O, Manning MF. Fatty streaks in the intima of arteries. Journal of Pathology and Bacteriology 16: 211–220, 1911

    Article  Google Scholar 

  • Kolata GB, Marx JL. Epidemiology of heart disease: searches for causes. Science 174: 509–512, 1976

    Article  Google Scholar 

  • Landt KW, Campaigne BN, James FW, Sperling MA. Effects of exercise training on insulin sensitivity in adolescents with type I diabetes. Diabetes Care 8: 461–465, 1985

    Article  PubMed  CAS  Google Scholar 

  • Laskarzewski P, Morrison JA, de Grott I, Kelly KA, Mellies J, et al. Lipid and lipoprotein tracking in 108 children over a four-year period. Pediatrics 64: 584–591, 1979

    PubMed  CAS  Google Scholar 

  • Larsson Y. Physical performance and the young diabetic. In Boileau (Ed.) Advances in pediatric sport sciences, pp. 131–156, Human Kinetics Publishers, Illinois, 1984

    Google Scholar 

  • Larsson Y, Persson B, Sterky G, Thoren C. Functional adaptations to vigorous training and exercise in diabetic and non-diabetic adolescents. Journal of Applied Physiology 19: 629–635, 1964a

    PubMed  CAS  Google Scholar 

  • Larsson Y, Persson B, Sterky G, Thoren C. Effect of exercise on blood-lipids in juvenile diabetes. Lancet 1: 350–355, 1964b

    Article  PubMed  CAS  Google Scholar 

  • Lauer RM, Clarke WR. Immediate and long-term prognostic significance of childhood blood pressure levels. In Lauer & Shekelle (Eds) Childhood prevention of atherosclerosis and hypertension, Raven Press, New York, 1980

    Google Scholar 

  • Lauer RM, Conner WE, Leaverton PE, Reiter MA, Clarke WR. Coronary heart disease risk factors in school children: the Muscatine study. Journal of Pediatrics 86: 697–706, 1975

    Article  PubMed  CAS  Google Scholar 

  • Lawrence RD. The effects of exercise on insulin action in diabetes. British Medical Journal 1: 648–652, 1926

    Article  PubMed  CAS  Google Scholar 

  • Linder CW, Durant RH. Exercise, serum lipids, and cardiovascular disease-risk factors in children. Pediatric Clinics of North America 29: 1341–1354, 1982

    PubMed  CAS  Google Scholar 

  • Linder CW, Durant RH, Gray RG, Harkness JW. The effect of exercise in serum lipid levels in children. Clinical Research 27: 297, 1979

    Google Scholar 

  • Linder CW, Durant RH, Mahoney OM. The effect of physical conditioning on serum lipids and lipoproteins in white male adolescents. Medicine and Science in Sports and Exercise 15: 232–236, 1983

    Article  PubMed  CAS  Google Scholar 

  • Lipid Research Clinic Program. The lipid research clinics coronary primary prevention trial results. I. Reduction in incidence of coronary heart disease. Journal of the American Medical Association 251: 351–364, 1984

    Article  Google Scholar 

  • Lussier L, Buskirk ER. Effect of an endurance training regimen on assessment of work capacity on prepubertal children. Annals of New York Academy of Science 301: 734–747, 1977

    Article  CAS  Google Scholar 

  • Macek M, Rutenfranz J, Lange Anderson K, Masopust J, Vavra J, et al. Favourable levels of cardiovascular health and risk indicators during childhood and adolescence. European Journal of Pediatrics 144: 360–367, 1985

    Article  PubMed  CAS  Google Scholar 

  • Mahon AD, Vaccaro P. Ventilatory threshold and V̇O2max changes in children following endurance training. Medicine and Science in Sports and Exercise, in press, 1989

    Google Scholar 

  • Marble A, White P, Bradley RF, Krall LP (Eds). Joslin’s diabetes mellitus, Lea & Febiger, Pennsylvania, 1971

    Google Scholar 

  • Massicotte DR, MacNab RBJ. Cardiorespiratory adaptation to training at specified intensities in children. Medicine and Science in Sports 6: 242–246, 1974

    PubMed  CAS  Google Scholar 

  • Mason JK. Asymptomatic disease of coronary arteries in young men. British Medical Journal 2: 1234–1237, 1963

    Article  PubMed  CAS  Google Scholar 

  • Mayer J. Overweight: causes, cost and control. Prentice Hall, New Jersey, 1968

    Google Scholar 

  • McDonough J, Hands C, Subb S, Gamson GE. Coronary heart disease among negroes and whites in Evans county. Journal of Chronic Diseases 18: 443–468, 1965

    Article  CAS  Google Scholar 

  • McGill HC, Geer JC, Strong JP. Natural history of human atherosclerotic lesions: In Sandier & Bourne (Eds) Atherosclerosis and its origins, pp. 39–66, Academic Press, New York, 1963

    Google Scholar 

  • McHenry PL, Fans JV, Jordan JW, Morris SN. Comparative study of cardiovascular function and ventricular premature complexes in smokers and nonsmokers during maximal treadmill exercise. American Journal of Cardiology 39: 493–498, 1977

    Article  PubMed  CAS  Google Scholar 

  • McKenzie TL, Buono M, Nelson J. Modification of coronary heart disease (CHD) risk factors in obese boys through diet and exercise. American Corrective Therapy Journal 38: 35–37, 1984

    PubMed  CAS  Google Scholar 

  • McNamara JJ, Molot MA, Stremple JF, Cutting RT. Coronary artery disease in combat casualties in Vietnam. Journal of the American Medical Association 216: 1185–1187, 1971

    Article  PubMed  CAS  Google Scholar 

  • Miller N. The evidence for the antiatherogenicity of high density lipoprotein in a man. Lipids 13: 914–919, 1978

    Article  PubMed  CAS  Google Scholar 

  • Mjos OD, Thelle DS, Forde OH, Vik-Mo H. Family study of high density lipoprotein cholesterol and the relation to age and sex. Acta Medica Scandinavica 201: 323–329, 1977

    Article  PubMed  CAS  Google Scholar 

  • Mocellin R, Wasmund U. Investigation on the influence of a running-training program on the cardiovascular and motor performance capacity in 53 boys and girls of a second and third primary school class. In Bar-Or (Ed.) Pediatric work physiology: Proceedings of the 4th International Symposium, pp. 279–285, Wingate Institute, Israel, 1973

    Google Scholar 

  • Montoye HJ. Physical activity and health: an epidemiologic study of an entire community. Prentice Hall, New Jersey, 1975

    Google Scholar 

  • Montoye HJ. Physical activity, physical fitness, and heart disease risk factors in children. In Stull & Eckert (Eds) Effects of physical activity on children, pp. 127–152, Human Kinetics Publishers, Illinois, 1986

    Google Scholar 

  • Montoye HJ, Block W, Keller JB, Willis PW. Glucose tolerance and physical fitness: an epidemiologic study in an entire community. European Journal of Applied Physiology 37: 237–242, 1977

    Article  CAS  Google Scholar 

  • Montoye HJ, Mikkelsen WM, Metzner HL. Physical activity, fatness, and serum uric acid. Journal of Sports Medicine and Physical Fitness 16: 253–260, 1976

    PubMed  CAS  Google Scholar 

  • Morrison JA, Kelly KA, Mellies MJ, deGroot I, Glueck CJ. Parent-child associations at upper and lower ranges of plasma cholesterol and triglyceride levels. Pediatrics 62: 468–477, 1978

    PubMed  CAS  Google Scholar 

  • Morrison JA, deGroot I, Edwards BK, Kelly KA, Mellies MJ. Lipids and lipoproteins in 927 school children, ages 6 to 17 years. Pediatrics 62: 990–995, 1978

    PubMed  CAS  Google Scholar 

  • Morrison JA, deGroot I, Kelly KA, Mellies MJ, Khoury P, et al. Black-white differences in plasma lipoproteins in Cincinnati school children. Metabolism Clinical and Experimental 28: 241–245, 1979

    Article  PubMed  CAS  Google Scholar 

  • Morrison JA, Horvitz R, Khoury P, Laskarzewsa P, Gartside PS. Parental history of coronary heart disease risk factor variables in their adult children. Preventive Medicine 9: 773–786, 1980

    Article  PubMed  CAS  Google Scholar 

  • Nora JJ. Identifying the child at risk for coronary heart disease as an adult: a strategy for prevention. Journal of Pediatrics 97: 706–711, 1980a

    Article  PubMed  CAS  Google Scholar 

  • Nora JJ, Lortscher RM, Spangler RD, Nora AH, Kimberlings WJ. Genetic epidemiology of early onset ischemic heart disease. Circulation 61: 503–508, 1980b

    Article  PubMed  CAS  Google Scholar 

  • Nutrition Committee, Canadian Paediatric Society. Adolescent nutrition: 3. Obesity. Canadian Medical Association Journal 129: 549–551, 1983

    Google Scholar 

  • Oscai LB. The role of exercise in weight control. In Wilmore (Ed.) Exercise and sport sciences reviews, Academic Press, New York, 1973

    Google Scholar 

  • Paffenbarger RS, Hale WE. Work activity and coronary heart mortality. New England Journal of Medicine 292: 545–550, 1975

    Article  PubMed  CAS  Google Scholar 

  • Paffenbarger RS, Hale WE, Brand RJ, Hyde RT. Work-energy level, personal characteristics, and fatal heart attack: a birth cohort effect. American Journal of Epidemiology 105: 200–213, 1977

    PubMed  Google Scholar 

  • Paffenbarger RS, Wing AL, Hyde RT. Physical activity as an index of heart attack risk in college alumni. American Journal of Epidemiology 108: 161–175, 1978

    PubMed  Google Scholar 

  • Parizkova J. Somatic development and body composition changes in adolescent boys differing in physical activity and fitness: a longitudinal study. Anthropologie 10: 3–36, 1972

    Google Scholar 

  • Parizkova J. Particularities of lean body mass and fat development in growing boys as related to their motor activity. Acta Paediatrica Belgique 28 (Suppl.): 233–243, 1974

    Google Scholar 

  • Parizkova J. Physical training in weight reduction of obese adolescents. Annals of Clinical Research 34: 63–68, 1982

    Google Scholar 

  • Parizkova J, Vaneckova M, Spryranova S, Vamberova M. Body composition and fitness in obese children before and after special treatment. Acta Paediatrica Scandinavica 217 (Suppl.): 80–85, 1971

    Article  PubMed  CAS  Google Scholar 

  • Pate RR, Blair SN. Exercise and the prevention of atherosclerosis: pediatric implications. In Strong (Ed.) Atherosclerosis: its pediatric aspects, pp. 252–286, Grune & Stratton, New York, 1978

    Google Scholar 

  • Pollock ML. The quantification of endurance training programs. In Wilmore (Ed.) Exercise and sport sciences reviews, pp. 155–188, Academic Press, New York, 1973

    Google Scholar 

  • Pollock ML, Wilmore JH, Fox SM. Exercise in health and disease, W.B. Saunders Co., Pennsylvania, 1984

    Google Scholar 

  • Poskitt EM, Colte TJ. Do babies stay fat? British Medical Journal 1: 7–9, 1977

    Article  PubMed  CAS  Google Scholar 

  • Rainville S, Vaccaro P. The effects of menopause and training on serum lipids. International Journal of Sports Medicine 5: 137–141, 1984

    Article  PubMed  CAS  Google Scholar 

  • Richmond D, Blyler E, Linscheid T. The obese child. American Family Physician 28: 129–134, 1983

    PubMed  CAS  Google Scholar 

  • Rigal RD, Lovell FW, Townsend FM. Pathologic findings in the cardiovascular systems of military flying personnel. American Journal of Cardiology 6: 19–25, 1960

    Article  Google Scholar 

  • Rolland-Cachera M, Deheeger M, Bellisle F, Sempe M, Guilloud-Bataille M, et al. Adiposity rebound in children: a simple indicator for predicting obesity. American Journal of Clinical Nutrition 39: 129–135, 1984

    PubMed  CAS  Google Scholar 

  • Rowland TW. Aerobic response to endurance training in prepubescent children: a critical analysis. Medicine and Science in Sports and Exercise 17: 493–497, 1985

    Article  PubMed  CAS  Google Scholar 

  • Saris WHM, Binkhurst RA, Cramwinckel AB, Van Der Veen-Hezemans AM, van Waesberghe F. Evaluation of somatic effects of health education program for school children. Bibliotheca Nutrito et Dieta 27: 77–84, 1979

    Google Scholar 

  • Saris WMH, Binkhurst RA, Cramwinckel AB, van Waesberghe F, Van Der Veen-Hezeman AM. The relationship between working performance, daily physical activity, fatness, blood lipids and nutrition in school children. In Berg & Ericksson (Eds) Children and exercise IX, pp. 166–174, University Park Press, Maryland, 1980

    Google Scholar 

  • Savage PJ, Hamman RF, Bartha G, Dippe SE, Miller M, et al. Serum cholesterol levels in American (Pima) Indian children and adolescents. Pediatrics 58: 274–282, 1976

    PubMed  CAS  Google Scholar 

  • Savage MP, Petratis MM, Thomson WH, Berg K, Smith JL, et al. Exercise training effects on serum lipids of prepubescent boys and adult men. Medicine and Science in Sports and Exercise 18: 197–204, 1985

    Google Scholar 

  • Shestowsky B. Ego identity development and obesity in adolescent girls. Adolescence 18: 551–559, 1983

    PubMed  CAS  Google Scholar 

  • Smoking and Health: A report of the Surgeon General, Washington, D.C., Department of Health, Education and Welfare, 1979

    Google Scholar 

  • Srinivasian SR, Frericks RR, Berenson GS. Serum lipids and lipoproteins in children. In Strong (Ed.) Atherosclerosis, its pediatric aspects, Grune & Stratton, New York, 1978

    Google Scholar 

  • Stamber R, Stamber J, Riedlinger WF, Algera G, Roberts RH. Family (parental) history and prevalence of hypertension. Journal of the American Medical Association 241: 43–46, 1979

    Article  Google Scholar 

  • Stamler J. Epidemiology of coronary heart disease. Medical Clinics of North America 57: 5–46, 1973

    PubMed  CAS  Google Scholar 

  • Stamler J. Lifestyles, major risk factors, proof and public policy. Circulation 58: 3–19, 1978

    Article  PubMed  CAS  Google Scholar 

  • Stark O, Atkins E, Wolff OH, Douglas JWB. Longitudinal study of obesity in the national survey of health and development. British Medical Journal 283: 13–17, 1981

    Article  PubMed  CAS  Google Scholar 

  • Stefanski PA, Heald FP, Mayer J. Caloric intake in relation to energy output in obese and non-obese adolescent boys. American Journal of Clinical Nutrition 7: 55–62, 1959

    Google Scholar 

  • Stewart KJ, Gutin B. Effects of physical training on cardiorespiratory fitness in children. Research Quarterly 47: 110–120, 1976

    PubMed  CAS  Google Scholar 

  • Streja D, Steiner G, Kwiterovich PO. Plasma high-density lipoproteins and ischemic heart disease: studies in a large kindred with familial hypercholesterolemia. Annals of Internal Medicine 89: 871–880, 1978

    PubMed  CAS  Google Scholar 

  • Strong JP, McGill HC. The pediatric aspects of atherosclerosis. Journal of Atherosclerosis Research 9: 251–265, 1969

    Article  PubMed  CAS  Google Scholar 

  • Strong JP, Eggen DA, Oalmann MC. The natural history, geographic pathology and epidemiology of atherosclerosis. In Wisher & Geer (Eds) The pathogenesis of atherosclerosis, pp. 20–40, Williams & Wilkins, Maryland, 1972

    Google Scholar 

  • Strong WB. Is atherosclerosis really a pediatric problem? Resident and Staff Physician 1: 55, 1977

    Google Scholar 

  • Sundberg S, Elovainio R. Cardiorespiratory function in competitive endurance runners aged 12–16 years compared with ordinary boys. Acta Paediatrica Scandinavica 11: 987–992, 1982

    Article  Google Scholar 

  • Taylor HL, Klepetar E, Keys A, Parlin W, Blackburn H, et al. Death rates among physically active and sedentary employees of the railroad industry. American Journal of Public Health 52: 1697–1707, 1962

    Article  PubMed  CAS  Google Scholar 

  • Thompson JK, Jarvie GJ, Lahey BB, Cureton KJ. Exercise and obesity: etiology, physiology and intervention. Psychological Bulletin 91: 55–79, 1982

    Article  PubMed  CAS  Google Scholar 

  • Thorland WG, Gilliam TB. Comparison of serum lipids between habitually high and low active pre-adolescent males. Medicine and Science in Sports and Exercise 13: 316–321, 1981

    PubMed  CAS  Google Scholar 

  • Tyroler H, Heyden S, Harnes C. Weight and hypertension: Evans county studies of blacks and whites. In Parel (Ed.) Epidemiology and control of hypertension, Grune & Stratton, New York, 1975

    Google Scholar 

  • Vaccaro P, Clarke DH. Cardiorespiratory alteration in 9 to 11 year old children following a season of competitive swimming. Medicine and Science in Sports 10: 204–207, 1978

    PubMed  CAS  Google Scholar 

  • Vaccaro P, Clarke DH, Morris AF. Physiological characteristics of young well-trained swimmers. European Journal of Applied Physiology 44: 61–66, 1980

    Article  CAS  Google Scholar 

  • Vaccaro P, Galioto FM, Bradley LM, Hansen DA, Vaccaro J. Development of a cardiac rehabilitation programme for children. Sports Medicine 1: 205–211, 1984

    Article  Google Scholar 

  • Vaccaro P, Mahon AD. Cardiorespiratory responses to endurance training in children. Sports Medicine 4: 352–363, 1987

    Article  PubMed  CAS  Google Scholar 

  • Vaccaro P, Paffenbarger A. Resting and exercise respiratory function in young female child runners. Journal of Sports Medicine and Physical Fitness 22: 102–109, 1982

    PubMed  CAS  Google Scholar 

  • Vaccaro P, Zauner CW, Updyke WF. Resting and exercise respiratory function in well-trained child swimmers. Journal of Sports Medicine and Physical Fitness 17: 297–306, 1977

    PubMed  CAS  Google Scholar 

  • Valimaki I, Hursti ML, Pihlaskoski L, Viikari J. Exercise performance and serum lipids in relationship to physical activity in school children. International Journal of Sports Medicine 1: 132–136, 1980

    Article  CAS  Google Scholar 

  • Velican D, Velican C. Study of fibrous plaques occurring in coronary arteries of children. Atherosclerosis 33: 201–215, 1979

    Article  PubMed  CAS  Google Scholar 

  • Velican D, Velican C. Atherosclerotic involvement of the coronary arteries of adolescents and young adults. Atherosclerosis 36: 449–460, 1980

    Article  PubMed  CAS  Google Scholar 

  • Vlasek IW, Hart SS, Seitz G. Fatness changes in adolescent summer campers. Medicine and Science in Sports and Exercise 15: 180, 1983

    Article  Google Scholar 

  • Vobecky J, Vobecky J, Shapcott D, Demers P. Nutrient intake patterns and nutritional status with regard to relative weight in early infancy. American Journal of Clinical Nutrition 38: 730–738, 1983

    PubMed  CAS  Google Scholar 

  • Voller RD, Strong WB. Pediatric aspects of atherosclerosis. American Heart Journal 101: 815–836, 1981

    Article  PubMed  Google Scholar 

  • Wanne O, Viikari J, Valimaki I. Physical performance and serum lipids in 14–16 year old trained, normally active, and inactive children. In Ilmarinen & Valimaki (Eds) Children and sport, Springer-Verlag, Berlin, 1984

    Google Scholar 

  • Waxman M, Stunkard A. Caloric intake and expenditure of obese boys. Journal of Pediatrics 96: 187–193, 1980

    Article  PubMed  CAS  Google Scholar 

  • Webber LS, Baugh JG, Cresonta JL, Berenson GS. Transition of cardiovascular risk factors from adolescence to young adulthood: the Bogalusa post high school study. Circulation (Suppl. II): 111–160, 1983a

    Google Scholar 

  • Webber LS, Cresanta JL, Voors AW. Tracking of cardiovascular disease risk factors variables in school-age children. Journal of Chronic Diseases 36: 647–660, 1983b

    Article  PubMed  CAS  Google Scholar 

  • Weil WB. Current controversies in childhood obesity. Journal of Pediatrics 91: 175–187, 1977

    Article  PubMed  Google Scholar 

  • Wenninger M, Widhalm K, Strobl W, Schernthaner G. Childhood obesity: serum lipoproteins, glucose and insulin concentrations after an oral glucose load. Artery 8: 185–190, 1980

    Google Scholar 

  • Williams RS, Toque EE, Lewis JL, Barton T, Stead NW, et al. Physical conditioning augments the fibrinolytic response to venous occlusion in healthy adults. New England Journal of Medicine 302: 981–991, 1980

    Article  Google Scholar 

  • Wilmore JH. Training for sport and activity: the physiological basis of the conditioning process. Allyn and Bacon Inc., Boston, 1982

    Google Scholar 

  • Wilmore JH, McNamara JJ. Prevalence of coronary heart disease risk factors in boys, 8 to 12 years of age. Journal of Pediatrics 84: 527–533, 1974

    Article  PubMed  CAS  Google Scholar 

  • Wolman P. Feeding practices in infancy and prevalence of obesity in preschool children. Journal of the American Dietetic Association 84: 436–438, 1984

    PubMed  CAS  Google Scholar 

  • Wood PD, Haskell WL. The effect of exercise on plasma high density lipoproteins. Lipids 14: 417–427, 1979

    Article  PubMed  CAS  Google Scholar 

  • Ylitalo VM. Exercise performance and serum lipids in obese school children before and after reconditioning program. In Ilmarinen & Valimaki (Eds) Children and sport, pp. 247–254, Springer-Verlag, Berlin, 1984

    Chapter  Google Scholar 

  • Yoshida T, Ishiko I, Muraoka I. Effects of endurance training on cardiorespiratory functions of 5 year old children. International Journal of Sports Medicine 1: 91–94, 1980

    Article  Google Scholar 

  • Zeek P. Juvenile atherosclerosis. Archives of Pathology 10: 417–446, 1930

    Google Scholar 

  • Zinserling WD. Untersuchungen uber atherosklerose. 2. uber die aortaverfettung ber kindern. Vierchow’s Archiv fur Pathologische Anatomie und Physiologie 255: 677–705, 1925

    Google Scholar 

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  1. Exercise Science Laboratory, University of Maryland, College Park, Maryland, 20742, USA

    Paul Vaccaro & Anthony D. Mahon

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Vaccaro, P., Mahon, A.D. The Effects of Exercise on Coronary Heart Disease Risk Factors in Children. Sports Med 8, 139–153 (1989). https://doi.org/10.2165/00007256-198908030-00002

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