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Licensed Unlicensed Requires Authentication Published by De Gruyter July 16, 2014

Effect of depth on shear-wave elastography estimated in the internal and external cervical os during pregnancy

  • Edgar Hernandez-Andrade EMAIL logo , Alma Aurioles-Garibay , Maynor Garcia , Steven J. Korzeniewski , Alyse G. Schwartz , Hyunyoung Ahn , Alicia Martinez-Varea , Lami Yeo , Tinnakorn Chaiworapongsa , Sonia S. Hassan and Roberto Romero EMAIL logo

Abstract

Aim: To investigate the effect of depth on cervical shear-wave elastography.

Methods: Shear-wave elastography was applied to estimate the velocity of propagation of the acoustic force impulse (shear wave) in the cervix of 154 pregnant women at 11–36 weeks of gestation. Shear-wave speed (SWS) was evaluated in cross-sectional views of the internal and external cervical os in five regions of interest: anterior, posterior, lateral right, lateral left, and endocervix. Distance from the center of the ultrasound (US) transducer to the center of each region of interest was registered.

Results: In all regions, SWS decreased significantly with gestational age (P=0.006). In the internal os, SWS was similar among the anterior, posterior, and lateral regions and lower in the endocervix. In the external os, the endocervix and anterior regions showed similar SWS values, lower than those from the posterior and lateral regions. In the endocervix, these differences remained significant after adjustment for depth, gestational age, and cervical length. SWS estimations in all regions of the internal os were higher than those of the external os, suggesting denser tissue.

Conclusion: Depth from the US probe to different regions in the cervix did not significantly affect the SWS estimations.


Corresponding authors: Roberto Romero, MD, D. Med. Sci., and Edgar Hernandez-Andrade, MD, PhD, Perinatology Research Branch, NICHD/NIH/DHHS, Wayne State University/Hutzel Women’s Hospital, 3990 John R, Box 4, Detroit, MI, 48201 USA, Tel.: +1-313-993-2700, Fax: +1-313-993-2694, E-mail: ;

Acknowledgements

This research was supported, in part, by the Perinatology Research Branch, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services (NICHD/NIH), and, in part, with Federal funds from NICHD, NIH under contract no. HHSN275201300006C. The ultrasound experience and technical support of senior Registered Diagnostic Medical Sonographers (RDMS), Catherine Ducharme, Denise Haggerty, and Cara Staszewski are gratefully acknowledged.

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The authors stated that there are no conflicts of interest regarding the publication of this article.

Received: 2014-2-28
Accepted: 2014-5-19
Published Online: 2014-7-16
Published in Print: 2014-9-1

©2014 by De Gruyter

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