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Licensed Unlicensed Requires Authentication Published by De Gruyter June 1, 2005

Intravenous immunoglobulin (IVIG): modes of action in the clinical management of recurrent pregnancy loss (RPL) and selected autoimmune disorders

  • Charles O. A. Omwandho , Susanne E. M. Gruessner , Timothy K. Roberts and Hans Rudolf Tinneberg
From the journal Clinical Chemistry and Laboratory Medicine (CCLM)
https://doi.org/10.1515/CCLM.2004.065

Abstract

Recurrent pregnancy loss has been associated with autoimmune responses to membrane phospholipids and alloimmune reactions against paternally derived molecules on the trophoblast. The problem is psychologically and economically stressful as it undermines the capacity of some couples to reproduce and participate effectively in the day-to-day economic activities. This article reviews the adoption of intravenous immunoglobulin as a form of therapy for the clinical management of recurrent pregnancy loss and of selected autoimmune disorders. Side effects, contraindications and safety of use are discussed.

Published Online: 2005-6-1
Published in Print: 2004-4-5

Copyright © 2004 by Walter de Gruyter GmbH & Co. KG

From the journal
Clinical Chemistry and Laboratory Medicine (CCLM)
Clinical Chemistry and Laboratory Medicine (CCLM)
Volume 42 Issue 4
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Intravenous immunoglobulin (IVIG): modes of action in the clinical management of recurrent pregnancy loss (RPL) and selected autoimmune disorders
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