Abstract
ABSTRACT. Glucose formation from uniformly labeled 14C-lactate was studied in the small intestinal mucosa of rats and rabbits. It was found to occur in infant but not in adult (weaned) animals and to be increased by the presence of dibutyryl cyclic AMP or tetradecyl glycidic acid. Similarly the formation of glyceride glycerol was enhanced by tetradecyl glycidic acid but not by glucagon or cyclic AMP. The glycogen content of the intestinal mucosa was always low, but increased significantly at the time of weaning. It is suggested that gluconeogenesis occurs in the small intestinal mucosa of infant rodents to supply glucose to the muscular part of the small intestine.
Similar content being viewed by others
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hahn, P., Wei-Ning, H. Gluconeogenesis from Lactate in the Small Intestinal Mucosa of Suckling Rats. Pediatr Res 20, 1321–1323 (1986). https://doi.org/10.1203/00006450-198612000-00027
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1203/00006450-198612000-00027
This article is cited by
-
Radioactivity Reduction of 2-Deoxy-2-[18F] Fluoro-D-Glucose by Milk and Ursodeoxycholic Acid in Preclinical Study
Nuclear Medicine and Molecular Imaging (2020)
-
Bacterial community structure and functional contributions to emergence of health or necrotizing enterocolitis in preterm infants
Microbiome (2013)