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Measurements of the anatomical distribution of erythemal ultraviolet: a study comparing exposure distribution to the site incidence of solar keratoses, basal cell carcinoma and squamous cell carcinoma

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Abstract

Measurements of anatomical UV exposure distribution were made using miniaturized polysulfone dosimeters over a four year period between 2005 and 2008 in Toowoomba, Australia (28° S, 152° E). Anatomical UV exposures were expressed relative to the horizontal plane ambient UV. The UV exposures were compared with existing data detailing the anatomical distribution of basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and solar keratoses (SK). Surface UV exposures to unprotected skin surfaces have been presented for each of the face, neck, arm, hand and leg assessing a total of 1453 body sites (2491 measurements). Measured exposures are presented for the human facial region to a resolution of 5 mm. The median anatomical UV expressed relative to the horizontal plane ambient UV for each of the face, neck, forearm, hand and leg regions of the body varied from 26%, 23%, 13%, 30% and 12% respectively in the 0°–30° SZA range; 39%, 36%, 17%, 35% and 23% in the 30°–50° SZA range; and 48%, 59%, 41%, 42% and 47% in the 50°–80° SZA range. Detailed positions of UV exposure measured over the face, neck, arm, hand and leg were more closely related to NMSC incidence data for the face and upper limbs. Further analysis with existing facial BCC and SK density data did not however show a direct relationship with the measured UV exposures highlighting the importance of other factors influencing the causation and localisation of facial NMSC.

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References

  1. T. L. Diepgen, V. Mahler, The epidemiology of skin cancer, Br. J. Dermatol., 2002, 146s61, 1–6.

    Article  Google Scholar 

  2. E. Konishi, Y. Yoshizawa, Estimation of depth of basal cell layer of skin for radiation protection, Radiat. Prot. Dosim., 1985, 111, 29–33.

    Google Scholar 

  3. B. A. Raasch, P. G. Buettner, C. Garbe, Basel cell carcinoma: histological classification and body-site distribution, Br. J. Dermatol., 2006, 155, 401–407.

    Article  CAS  Google Scholar 

  4. M. P. Staples, M. Elwood, R. C. Burton, J. L. Williams, R. Marks, G. G. Giles, Non-melanoma skin cancer in Australia: the 2002 national survey and trends since 1985, Med. J. Aust., 2006, 184, 6–10.

    Article  Google Scholar 

  5. F. R. deGruijl, Skin cancer and solar UV radiation, Eur. J. Cancer, 1999, 3514, 2003–2009.

    Article  CAS  Google Scholar 

  6. J. A. Parrish, K. F. Jaenicke, R. R. Anderson, Erythema and melanogenesis action spectra of normal human skin, Photochem. Photobiol., 1982, 36, 187–191.

    Article  CAS  Google Scholar 

  7. M. Staples, R. Marks, G. Giles, Trends in the incidence of non-melanocytic skin cancer (NMSC) treated in Australia 1985–1995: Are primary prevention programs starting to have an effect?, Int. J. Cancer, 1998, 782, 144–148.

    Article  CAS  Google Scholar 

  8. R. Marks, G. Rennie, T. Selwood, The relationship of basal cell carcinomas and squamous cell carcinomas to solar keratoses, Arch. Dermatol., 1988, 1247, 1039–1042.

    Article  CAS  Google Scholar 

  9. C. A. Frost, A. C. Green, Epidemiology of solar keratoses, Br. J. Detmatol., 1994, 1314, 455–464.

    Article  CAS  Google Scholar 

  10. R. Marks, D. Rennie, T. S. Selwood, Malignant transformation of solar keratose to squamous cell carcinoma, Lancet, 1988, 3318589, 795–797.

    Article  Google Scholar 

  11. J. Röwert-Huber, M. J. Patel, T. Forschner, C. Ulrich, J. Eberle, H. Kerl, W. Sterry, E. Stockfleth, Actinic keratosis is an early in situ squamous cell carcinoma: a proposal for reclassification, Br. J. Dermatol., 2007, 156, 8–12.

    Article  Google Scholar 

  12. T. D. Nguyen, V. Siskind, L. Green, C. Frost, A. Green, Ultraviolet radiation, melanocytic naevi and their dose-response relationship, Br. J. Dermatol., 1997, 137, 91–95.

    Article  CAS  Google Scholar 

  13. B. L. Diffey, T. J. Tate, A. Davis, Solar dosimetry of the face: the relationship of natural ultraviolet radiation exposure to basal cell carcinoma localisation, Phys. Med. Biol., 1979, 24, 931–939.

    Article  CAS  Google Scholar 

  14. R. H. Brodkin, A. W. Kopf and R. Andrade, Basal-cell epithelioma and elastosis: a comparison of distribution, in The Biologic Effects of Ultraviolet Radiation: with Emphasis on the Skin, ed. F. Urbach, Pergamon, New York, 1969, pp. 581–618.

  15. D. K. Pearl, E. L. Scott, The anatomical distribution of skin cancers, Int. J. Epidemiol., 1986, 154, 502–506.

    Article  CAS  Google Scholar 

  16. A. Kricker, D. R. English, P. L. Randell, P. J. Heenan, C. D. Clay, T. A. Delaney, B. K. Armstrong, Skin cancer in Geraldton, Western Australia: a survey of incidence and prevalence, Med. J. Aust., 1990, 1528, 399–407.

    Article  CAS  Google Scholar 

  17. B. Raasch, R. Maclennan, I. Wronski, I. Robertson, Body site specific incidence of basal and squamous cell carcinoma in an exposed population, Townsville, Australia, Mutat. Res., 1998, 422, 101–106.

    Article  CAS  Google Scholar 

  18. N. J. Downs, A. V. Parisi, Three dimensional visualisation of human facial exposure to solar ultraviolet, Photochem. Photobiol. Sci., 2007, 6, 90–98.

    Article  CAS  Google Scholar 

  19. B. L. Diffey, Ultraviolet radiation dosimetery with polysulphone film, in Radiation Measurement in Photobiology, ed. B. L. Diffey, Academic Press, London, 1989, pp. 135–159.

  20. A. Green, D. Battistutta, V. Hart, D. Leslie, G. Marks, G. Williams, P. Gaffney, P. Parsons, L. Hirst, C. Frost, E. Orrell, K. Durham, C. Lang, The Nambour skin cancer and actinic eye disease prevention trial: design and baseline characteristics of participants, Control. Clin. Trials, 1994, 15, 512–522.

    Article  CAS  Google Scholar 

  21. F. Urbach, Environmental risk factors for skin cancer, Recent Results Cancer Res., 1993, 128, 243–262.

    Article  CAS  Google Scholar 

  22. M. G. Kimlin, A. V. Parisi, J. C. F. Wong, The facial distribution of erythemal ultraviolet exposure in south east Queensland, Phys. Med. Biol., 1998, 43, 231–240.

    Article  CAS  Google Scholar 

  23. N. J. Downs, M. G. Kimlin, A. V. Parisi, J. J. McGrath, Modelling human facial UV exposure, Radiat. Prot. Australas., 2001, 173, 103–109.

    Google Scholar 

  24. Y. Scrivener, E. Grosshans, B. Cribier, Variation of basal cell carcinomas according to gender, age, location and histopathological subtype, Br. J. Dermatol., 2002, 147, 41–47.

    Article  CAS  Google Scholar 

  25. N. M. Richmond-Sinclair, N. Pandeya, R. S. Ware, R. E. Neal, G. M. Williams, J. C. van der Pols, A. C. Green, Incidence of basal cell carcinoma multiplicity and detailed anatomic distribution: longitudinal study of an Australian population, J. Invest. Dermatol., 2009, 1292, 323–328.

    Article  CAS  Google Scholar 

  26. G. G. Giles, R. Marks, P. Foley, Incidence of non-melanocytic skin cancer treated in Australia, Br. Med. J., 1988, 2966614, 13–17.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Faculty of Sciences, University of Southern Queensland, Toowoomba, 4350, Australia

    Nathan Downs & Alfio Parisi

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  1. Nathan Downs
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  2. Alfio Parisi
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Correspondence to Nathan Downs.

Additional information

Electronic supplementary information (ESI) available: Specific body site positions and measurements of UV exposure are provided for each of the face, neck, arm, hand and leg regions of the mannequin model. A total of 1453 individual site locations are illustrated. Mean exposures are provided for body sites in the 0°–30°, 30°–50° and 50°–80° solar zenith angle ranges. See DOI: 10.1039/b901741k

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Downs, N., Parisi, A. Measurements of the anatomical distribution of erythemal ultraviolet: a study comparing exposure distribution to the site incidence of solar keratoses, basal cell carcinoma and squamous cell carcinoma. Photochem Photobiol Sci 8, 1195–1201 (2009). https://doi.org/10.1039/b901741k

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  • DOI: https://doi.org/10.1039/b901741k

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