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Intravesicular instillation of E-aminocaproic acid for patients with adenovirus-induced hemorrhagic cystitis

Bone Marrow Transplantation volume 24, pages 1259–1260 (1999)Cite this article

Abstract

Hemorrhagic cystitis (HC) is a known complication of allogenic BMT. We report a case of a 28-year-old female with CML in chronic phase, which was treated with a matched unrelated donor (MUD) transplant, complicated by hemorrhagic cystitis on day +42 after the transplant. Adenovirus was isolated from the urine and she was treated with ribavirin, 1 g twice a day for 8 days. We report the use of Amicar (E-aminocaproic acid), 2.5 g solution as bladder instillation to treat the intractable hematuria.

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Authors and Affiliations

  1. Rush Cancer Institute, Section of Bone Marrow Transplant and Cell Therapy, Rush University, Chicago, IL, USA

    A Lakhani, A Raptis, D Frame, D Simpson, L Berkahn, S Mellon-Reppen & H Klingemann

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  1. A Lakhani
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  2. A Raptis
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  3. D Frame
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  4. D Simpson
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  5. L Berkahn
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  6. S Mellon-Reppen
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  7. H Klingemann
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Lakhani, A., Raptis, A., Frame, D. et al. Intravesicular instillation of E-aminocaproic acid for patients with adenovirus-induced hemorrhagic cystitis. Bone Marrow Transplant 24, 1259–1260 (1999). https://doi.org/10.1038/sj.bmt.1702040

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  • DOI: https://doi.org/10.1038/sj.bmt.1702040

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