Summary
In the first population-based analysis of certain epidemiologic features of primary malignancies of the small intestine in Germany, we used data from the Saarland Cancer Registry (1982–1993) and from the former National Cancer Registry of the German Democratic Republic (1976–1989). The age-standardized incidence rates for ages 0–74 years is 3.3–6.2 per million per year. The average incidence rates of the federal state Saarland are for men about 1.3 times and for women about 1.4 times the rate of the former German Democratic Republic. After the age of 30 years, the incidence rates increased with increasing age. Incidence rates for carcinoids levelled off after the age of 54 years. Rates for men were 35–40% higher than for women after adjusting for age. The risk for carcinomas, malignant carcinoids and malignant lymphoma were higher for men than for women.
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References
Ashley, S. W. & Wells, S. A. Jr (1988). Tumors of the small intestine. Semin Oncol 15: 116–128.
Becker, N. & Wahrendorf, J. (1998). Atlas of Cancer Mortality in the Federal Republic of Germany 1981–1990, Springer-Verlag: Berlin 10–12.
Brookes, V. S., Waterhouse, J. A. H. & Powell, D. J. (1968). Malignant lesions of the small intestine. A ten-year survey. Br J Surg 55: 405–410.
Bundesministerium für Landwirtschaft (1980). Statistisches Jahrbuch über Ernährung, Landwirtschaft und Forsten, Landwirtschaftsverlag Münster-Hiltrup: Münster 112–113.
Bundesministerium für Landwirtschaft (1997). Statistisches Jahrbuch über Ernährung, Landwirtschaft und Forsten, Landwirtschaftsverlag Münster-Hiltrup: Münster 146–147.
Chow, W. H., Linet, M. S., McLaughlin, J. K., Hsing, A. W., Co Chien, H. T. & Blot, W. J. (1993). Risk factors for small intestine cancer. Cancer Causes Control 4: 163–169.
Ellis, H. (1987). Tumours of the small intestine. Semin Oncol 3: 12–21.
Gabos, S., Berkel, J., Band, P., Robson, D. & Whittaker, H. (1993). Small bowel cancer in Western Canada. Int J Epidemiol 22: 198–206.
Hoffman, J. P., Taft, D. A., Wheelis, R. F. & Walker, J. H. (1977). Adenocarcinoma in regional enteritis of the small intestine. Arch Surg 112: 606–611.
WHO (1977). International Classification of Disease, 1975 revision, World Health Organization: Geneva
Jagelman, D. G., DeCosse, J. J. & Bussey, H. J. R. The Leeds Castle Polyposis Group: (1988). Upper gastrointestinal cancer in familial adenomatous polyposis. Lancet 1: 1149–1151.
Jones, B. A., Langer, B., Taylor, B. R. & Girotti, M. (1985). Periampullary tumors: which ones should be resected?. Am J Surg 149: 46–52.
Lightdale, C. J., Sternberg, S. S., Posner, G. & Sherlock, P. (1975). Carcinoma complicating Crohn’s disease. Am J Med 59: 262–268.
Lowenfels, A. B. & Sonni, A. (1977). Distribution of small bowel tumors. Cancer Lett 3: 83–86.
Matsuo, S., Toshifumi, E., Tsunoda, T., Kanematsu, T. & Shinozaki, T. (1994). Small bowel tumors: an analysis of tumor-like lesions, benign and malignant neoplasms. Eur J Surg Oncol 20: 47–51.
Parkin, D. M., Muir, C. S., Whelan, S. L., Gao, Y. T., Ferlay, J. & Powell, J. (eds) (1992). Cancer in Five Continents VI: IARC Scientific Publication: Lyon
Parkin, D. M., Whelan, S. L., Ferlay, J., Raymond, L. & Young, J. (eds) (1997). Cancer in Five Continents VII: IARC Scientific Publication: Lyon
Penn, I. (1987). Cancers following cyclosporine therapy. Transplantation 43: 32–35.
Percy, C., Van Holten, V. & Muir, C. (eds) (1990). International Classification of Diseases for Oncology, 2nd edn World Health Organization: Geneva
Richards, M. E., Rickert, R. R. & Nance, F. C. (1989). Crohn’s disease-associated carcinoma. Ann Surg 209: 764–773.
Selvin, S. (1996). Statistical Analysis of Epidemiological Data, 2nd edn Oxford University Press: New York 23–29.
Spigelman, A. D., Murday, V. & Phillips, R. K. S. (1989). Cancer and the Peutz-Jeghers syndrome. Gut 30: 1588–1590.
Spigelman, A. D., Williams, C. B., Talbot, I. C., Domizio, P. & Phillips, R. K. S. (1989). Upper gastrointestinal cancer in patients with familial adenomatous polyposis. Lancet 2: 783–785.
Statistisches Landesant Saarbrücken (1996). Morbidität und Mortalität an Bösartigen Neubildungen im Saarland 1993. Sonderheft Nr. 186, Reihe des Statistischen Landesamtes Saarland: Saarbrücken
Weiss, N. S. & Yang, C-P (1987). Incidence of histologic types of cancer of the small intestine. J Natl Cancer Inst 78: 653–656.
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Stang, A., Stegmaier, C., Eisinger, B. et al. Descriptive epidemiology of small intestinal malignancies: the German Cancer Registry experience. Br J Cancer 80, 1440–1444 (1999). https://doi.org/10.1038/sj.bjc.6690541
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DOI: https://doi.org/10.1038/sj.bjc.6690541
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