Biologic medications are highly efficacious in juvenile idiopathic arthritis. However, a recent study found that a subgroup of children treated with anti-TNF agents had persistent pain despite good disease control. This finding highlights the importance of monitoring pain symptoms during treatment with modern DMARDs.
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Consolaro, A., Ravelli, A. Juvenile idiopathic arthritis—are biologic agents effective for pain?. Nat Rev Rheumatol 9, 447–448 (2013). https://doi.org/10.1038/nrrheum.2013.108
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DOI: https://doi.org/10.1038/nrrheum.2013.108
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