Several lines of evidence both from experimental models and from clinical studies reveal that TNF-like ligand 1A (TL1A) and its interaction with death receptor 3 (DR3) is critically involved in the pathogenesis of rheumatoid arthritis and other autoimmune diseases.
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The author is supported by grants from Institut National de le Santé et de la Recherche Médicale, Université Pierre et Marie Curie and Université Paris Descartes.
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Bayry, J. TL1A in the inflammatory network in autoimmune diseases. Nat Rev Rheumatol 6, 67–68 (2010). https://doi.org/10.1038/nrrheum.2009.263
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DOI: https://doi.org/10.1038/nrrheum.2009.263
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