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Building bone from blood vessels

Mesenchymal stem cells (MSCs) can form different cell types in culture, but their potential to build new tissue in various disorders where tissue is damaged has not been realized. A study now shows how mature cells from blood vessels are a new source of MSCs that may be used to regenerate cartilage and bone (pages 1400–1406).

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Figure 1: Endothelial cell–derived MSCs may be a source of cells for regeneration of bone and cartilage tissues.

Marina Corral

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Correspondence to Edwin M Horwitz.

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Horwitz, E. Building bone from blood vessels. Nat Med 16, 1373–1374 (2010). https://doi.org/10.1038/nm1210-1373

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