Abstract
Objective:
The objective of this study is to compare complication rates between peripherally inserted central catheters (PICCs) and peripherally inserted non-central catheters (PINCCs) in the neonatal intensive care unit (NICU).
Study Design:
A retrospective, observational study was conducted. The PICCs were catheters whose tip terminated in the vena cavae, and PINCCs were defined as those whose tip fell short of this location. Complication rates were assessed using generalized estimating equations modeling.
Result:
A total of 91 PINCCs and 889 PICCs were placed in 750 neonates. In all, 44.0% of PINCCs had a major complication compared with 25.2% of PICCs (P=0.0001). The unadjusted (unadj.) complication rate among PINCCs was 51.7 per 1000 line days and 15.9 for PICCs (unadj. rate ratio: 3.25; 95% confidence interval (CI): 2.32, 4.55). After adjusting for multiple confounders, the risk remained significantly higher for PINCCs (adjusted odds ratio: 2.41; 95% CI: 1.33, 4.37).
Conclusion:
The rate of associated complications with the use of PINCCs in the NICU population is more than twice that of the PICCs.
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Acknowledgements
This publication was supported in part by the CTSA Grant Number UL1 RR024139 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH) and the NIH Roadmap for Medical Research, and by the Glaser Pediatric Research Network and Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Grant number HD07094. Dr Colacchio was supported by the NICHD Grant number T32 HD 07094. Its contents are solely the responsibility of the authors and do not necessarily represent the official view of NCRR, NIH or NICHD.
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Colacchio, K., Deng, Y., Northrup, V. et al. Complications associated with central and non-central venous catheters in a neonatal intensive care unit. J Perinatol 32, 941–946 (2012). https://doi.org/10.1038/jp.2012.7
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DOI: https://doi.org/10.1038/jp.2012.7
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