The use of biomarkers to predict human behaviour and psychiatric disorders raises social and ethical issues, which must be resolved by collaborative efforts.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
What are Mental Disorders? Exploring the Role of Culture in the Harmful Dysfunction Approach
Integrative Psychological and Behavioral Science Open Access 03 April 2024
-
Ethics of early detection of disease risk factors: A scoping review
BMC Medical Ethics Open Access 05 March 2024
-
Task-state skin potential abnormalities can distinguish major depressive disorder and bipolar depression from healthy controls
Translational Psychiatry Open Access 23 February 2024
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Moffitt, T. E. et al. J. Child Psychol. Psychiatry 49, 3–33 (2008).
Kirkwood, T., Bond, J., May, C., McKeith, I. & Teh, M. Foresight Mental Capital and Wellbeing Project. Mental Capital Through Life: Future Challenges (The Government Office for Science, London, 2008).
Goswami, U. Psychol. Educ. Rev. 29 (2), 2–8 (2005).
Maroney, T. A. The false promise of adolescent brain science in juvenile justice. The Gruter Institute Annual Conference (Squaw Valley, California, 18 May, 2009); at http://ssrn.com/abstract=1405367.
http://www.researchchannel.org/prog/displayevent.aspx?rid=4775
Brunner, H. G. Ciba Found. Symp. 194, 155–167 (2007).
Dinstein, I., Thomas, C., Behrmann, M. & Heeger, D. Curr. Biol. 18, R13–R18 (2008).
Swanson, J. et al. Neuropsychol. Rev. 17, 39–59 (2007).
Romeo, R. et al. Br. J. Psychiatry 188, 547–553 (2006).
Zito, J. M. et al. J. Child Adolesc. Psychopharmacol. 17, 195–204 (2007).
Parens, E. & Johnston, J. Child Adolesc. Psychiatry Ment. Health 2, 5 (2008).
Link, B. G. et al. Psychiatr. Serv. 52, 1621–1626 (2001).
Phelan, J. C. Trends Neurosci. 25, 430–431 (2002).
Phelan, J. Am. J. Med. Genet. 141B, 688 (2006).
Prainsack, B. et al. Nature 456, 34–35 (2008).
Silverman, C. Biosocieties 3, 325–341 (2008).
Collins, F. S. Nature Genet. 36, S13–S15 (2004).
Rose, N. Biosocieties 3, 423–439 (2008).
Thornicroft, G. Shunned: Discrimination Against People with Mental Illness (Oxford Univ. Press, 2006).
Goldstein, D. B. N. Engl. J. Med. 17, 1696–1698 (2009).
http://scienceblogs.com/geneticfuture/2009/04/personal_genomics_is_not_dead.php
Weisberg, D. S. et al. J. Cogn. Neurosci. 20, 470–477 (2008).
Seyffert, M. & Silva, R. Curr. Pediatr. Rev. 1, 17–24 (2005).
Vul, E., Harris, C., Winkielman, P. & Pashler. H . Perspect.Psychol. Sci. 4, 274–290 (2009).
Green, M. J. & Botkin, J. R. Ann. Intern. Med. 138, 571–575 (2003).
Schick, A. Am. J. Bioeth. 5, 36–38; W3–W4 (2005).
Foster, M. W. et al. J. Med. Ethics 32, 635–638 (2006).
Hudson, K., Javitt, G., Burke, W., Byers, P. & ASHG Social Issues Committee. Am. J. Hum. Genet. 81, 635–637 (2007).
Foster, M. W. & Sharp, R. R. Per. Med. 5, 399–404 (2008).
Kravitz, R. L. et al. J. Am. Med. Assoc. 293, 1995–2002 (2005).
Huniche, L. Outlines Crit. Soc. Studies 3, 35–52 (2001).
Lock, M. Curr. Anthropol. 46, S47–S70 (2005).
Lock, M. et al. Public Underst. Sci. 15, 277–300 (2006).
Viding, E., Blair, J. R., Moffitt, T. E. & Plomin, R. J. Child Psychol. Psychiatry 46, 592–597 (2004).
Decety, K. J., Michalska, Y. A. & Lahey, B. B. Biol. Psychol. 80, 203–211 (2008).
Beauchaine, T., Neuhaus, E., Brenner, S. & Gatzke-Kopp, L. Dev. Psychopathol. 20, 745–774 (2008).
Beauchaine, T. Biomark. Med. 3, 1–3 (2009).
Blair, R. J. R. Brain Cogn. 55, 198–208 (2004).
Biomarkers Definition Working Group. Clin. Pharmacol. Ther. 69, 89–95 (2001).
Caspi, A. et al. Science 297, 851–854 (2002).
Foley, D. L. et al. Arch. Gen. Psychiatry 61, 738–744 (2004).
Holtzman, P. Brain Res. Rev. 31, 350–356 (2000).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Singh, I., Rose, N. Biomarkers in psychiatry. Nature 460, 202–207 (2009). https://doi.org/10.1038/460202a
Published:
Issue Date:
DOI: https://doi.org/10.1038/460202a
This article is cited by
-
Ethics of early detection of disease risk factors: A scoping review
BMC Medical Ethics (2024)
-
Task-state skin potential abnormalities can distinguish major depressive disorder and bipolar depression from healthy controls
Translational Psychiatry (2024)
-
What are Mental Disorders? Exploring the Role of Culture in the Harmful Dysfunction Approach
Integrative Psychological and Behavioral Science (2024)
-
Precision behavioral phenotyping as a strategy for uncovering the biological correlates of psychopathology
Nature Mental Health (2023)
-
Smelling the Disease: Diagnostic Potential of Breath Analysis
Molecular Diagnosis & Therapy (2023)