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Infection in 2012

Mixed results of pre-exposure prophylaxis for HIV prevention

Nature Reviews Urology volume 10, pages 74–75 (2013)Cite this article

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In 2012, three trials of antiretroviral pre-exposure prophylaxis (PrEP) were reported, with conflicting results. Taken together with data from 2010 we now have two trials that showed no benefit and four studies that demonstrated moderate-to-high efficacy. Accordingly, it seems that PrEP might have a limited role for HIV prevention in individuals at high-risk of infection.

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Authors and Affiliations

  1. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 627 Washington Street, 2nd Floor, Baltimore, 21205, MD, USA

    Ronald H. Gray & Maria J. Wawer

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  1. Ronald H. Gray
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  2. Maria J. Wawer
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Correspondence to Ronald H. Gray.

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The authors declare no competing financial interests.

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Gray, R., Wawer, M. Mixed results of pre-exposure prophylaxis for HIV prevention. Nat Rev Urol 10, 74–75 (2013). https://doi.org/10.1038/nrurol.2012.259

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