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Rheumatoid arthritis

Guidelines for RA therapy—avoiding hamartia

Treatment guidelines are an increasingly prominent topic of discussion in medicine. Can rheumatologists avoid the 'fatal flaw' inherent in attempts to standardize treatment decision-making—in which overly strict adherence to guidelines might be pursued at the expense of optimizing individual patients' outcomes?

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References

  1. Smolen, J. S. et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann. Rheum. Dis. 69, 964–975 (2010).

    Article  CAS  Google Scholar 

  2. Kavanaugh, A. Guidelines in rheumatology: quo vadis. Nat. Rev. Rheumatol. 5, 423–424 (2009).

    Article  Google Scholar 

  3. Furst, D. E. et al. Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2009. Ann. Rheum. Dis. 69 (Suppl. 1), i2–i29 (2010).

    Article  CAS  Google Scholar 

  4. Saag, K. G. et al. American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis. Arthritis Rheum. 59, 762–784 (2008).

    Article  CAS  Google Scholar 

  5. Nam, J. L. et al. Current evidence for the management of rheumatoid arthritis with biological disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of RA. Ann. Rheum. Dis. 69, 976–986 (2010).

    Article  CAS  Google Scholar 

  6. Knevel, R. et al. Current evidence for a strategic approach to the management of rheumatoid arthritis with disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis. Ann. Rheum. Dis. 69, 987–994 (2010).

    Article  CAS  Google Scholar 

  7. Schoels, M. et al. Economic aspects of treatment options in rheumatoid arthritis: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis. Ann. Rheum. Dis. 69, 996–1004 (2010).

    Google Scholar 

  8. Gaujoux-Viala, C. et al. Current evidence for the management of rheumatoid arthritis with synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis. Ann. Rheum. Dis. 69, 1004–1009 (2010).

    Article  CAS  Google Scholar 

  9. Kavanaugh, A. et al. Effect of certolizumab pegol with methotrexate on home and work place productivity and social activities in patients with active rheumatoid arthritis. Arthritis Rheum. 61, 1592–1600 (2010).

    Article  Google Scholar 

  10. Timbie, J. W., Hayward, R. A. & Vijan, S. Variation in the net benefit of aggressive cardiovascular risk factor control across the US population of patients with diabetes mellitus. Arch. Intern. Med. 170, 1037–1044 (2010).

    Article  CAS  Google Scholar 

Download references

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Kavanaugh, A. Guidelines for RA therapy—avoiding hamartia. Nat Rev Rheumatol 6, 505–506 (2010). https://doi.org/10.1038/nrrheum.2010.138

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