Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Viral hepatitis

Treating hepatitis C in injection drug users

Subjects

A large proportion of hepatitis C in the developed world occurs in injection drug users. Treatment uptake in this population is low, despite the rising burden of HCV-related liver disease. Multiple barriers preclude the optimal care of hepatitis C in injection drug users, including low medication adherence and HCV re-infection.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Thomas, D. Global control of hepatitis C: where challenge meets opportunity. Nat. Med. 19, 850–858 (2013).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Robaeys, G. et al. Recommendations for the management of hepatitis C virus infection among people who inject drugs. Clin. Infect. Dis. 57 (Suppl. 2), 129–137 (2013).

    Article  Google Scholar 

  3. Hellard, M., Sacks-Davis, R. & Gold, J. Hepatitis C treatment for injection drug users: a review of the available evidence. Clin. Infect. Dis. 49, 561–573 (2009).

    Article  PubMed  Google Scholar 

  4. Melin, P. et al. Effectiveness of chronic hepatitis C treatment in drug users in routine clinical practice: results of a prospective cohort study. Eur. J. Gastroenterol. Hepatol. 22, 1050–1057 (2010).

    Article  CAS  PubMed  Google Scholar 

  5. Soriano, V. et al. Challenges and opportunities for hepatitis C drug development in HIV–HCV coinfected patients. AIDS 25, 2197–2208 (2011).

    Article  CAS  PubMed  Google Scholar 

  6. Altice, F., Kamarulzaman, A., Soriano, V., Schechter, M. & Friedland, G. Treatment of medical, psychiatric, and substance use comorbidities in people infected with HIV who use drugs. Lancet 376, 367–387 (2010).

    Article  PubMed  PubMed Central  Google Scholar 

  7. Soriano, V. et al. The changing face of hepatitis C in the new era of direct-acting antivirals. Antivir. Res. 97, 36–40 (2013).

    Article  CAS  PubMed  Google Scholar 

  8. Sulkowski, M. et al. Boceprevir versus placebo with pegylated interferon α-2b and ribavirin for treatment of hepatitis C virus genotype 1 in patients with HIV: a randomised, double-blind, controlled phase 2 trial. Lancet Infect. Dis. 13, 597–605 (2013).

    Article  CAS  PubMed  Google Scholar 

  9. Sulkowski, M. et al. Combination therapy with telaprevir for chronic hepatitis C virus genotype 1 infection in patients with HIV: a randomized trial. Ann. Intern. Med. 159, 86–96 (2013).

    PubMed  Google Scholar 

  10. Gallego, L., Barreiro, P. & López-Ibor, J. J. Diagnosis and clinical features of major neuropsychiatric disorders in HIV infection. AIDS Rev. 13, 171–179 (2011).

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vincent Soriano.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Soriano, V., Gallego, L. Treating hepatitis C in injection drug users. Nat Rev Gastroenterol Hepatol 10, 568–569 (2013). https://doi.org/10.1038/nrgastro.2013.165

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrgastro.2013.165

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing