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Supplementation of transport and freezing media with anti-apoptotic drugs improves ovarian cortex survival
Journal of Ovarian Research Open Access 12 February 2016
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References
Meirow, D. & Nugent, D. The effects of radiotherapy and chemotherapy on female reproduction. Hum. Reprod. Update 7, 535–543 (2001).
Morita, Y. et al. Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy. Nature Med. 6, 1109–1114 (2000).
Tilly, J.L. Commuting the death sentence: how oocytes strive to survive. Nature Rev. Mol. Cell Biol. 2, 838–848 (2001).
Nagasawa, H., Miyamoto, M. & Fujimoto M. Reproductivity in inbred strains of mice and project for their efficient production. Exp. Animals 22, 119–126 (1973).
Tarkowski, A.K. An air drying method for chromosome preparations from mouse eggs. Cytogenetics 5, 394–400 (1966).
Hassold, T. & Hunt, P. To err (meiotically) is human: The genesis of human aneuploidy. Nature Rev. Genet. 2, 280–291 (2001).
Hayashi, M., Morita, T., Kodama, Y., Sofuni, T. & Ishidate, M. Jr. The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange-coated slides. Mutat. Res. 245, 245–249 (1990).
Dubrova, Y.E. et al. Stage specificity, dose response, and doubling dose for mouse minisatellite germ-line mutation induced by acute radiation. Proc. Natl. Acad. Sci. USA 95, 6251–6255 (1998).
Perez, G.I., Knudson, C.M., Leykin, L., Korsmeyer, S.J. & Tilly J.L. Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. Nature Med. 3, 1228–1232 (1997).
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Paris, F., Perez, G., Fuks, Z. et al. Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring. Nat Med 8, 901–902 (2002). https://doi.org/10.1038/nm0902-901
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DOI: https://doi.org/10.1038/nm0902-901
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