Abstract
SIALIC acid residues are the principal constituents on the surface of plasma membranes1 and make the chief contribution to the negative charge of the cell surface2. A number of functional alterations of the cell can be induced by removal of the sialic acid from the surface membrane by neuraminidase3–6.
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References
Benedetti, E. L., and Emmelot, P., J. Cell Sci., 2, 499 (1967).
Ambrose, E. J., Prog. Biophys. Mol. Biol., 16, 241 (1966).
Sanford, B. H., Transplantation, 5, 1273 (1967).
Currie, G. A., Doornick, W. V., and Bagshawe, K. D., Nature, 219, 191 (1968).
Currie, G. A., and Bagshawe, K. D., Brit. J. Cancer, 22, 843 (1968).
Currie, G. A., and Bagshawe, K. D., Lancet, i, 708 (1967).
Weiss, L., Mayhew, E., and Ulrich, K., Lab. Invest., 15, 1304 (1966).
Lee, A., Proc. Soc. Exp. Biol. Med., 128, 891 (1968).
Baylor, M. E., Trans. NY Acad. Sci., 26, 1103 (1964).
Gesner, B., and Thomas, L., Science, 151, 590 (1966).
Kemp, R. B., Nature, 218, 1255 (1968).
Weiss, L., J. Cell Biol., 26, 735 (1965).
Woodruff, J. J., and Gesner, B. M., J. Exp. Med., 129, 551 (1969).
Brown, D. M., and Michael, A. F., Soc. Exp. Biol. Med., 131, 568 (1969).
Apffel, C. A., and Peters, J. H., J. Theoret. Biol., 26, 47 (1970).
Bagshawe, K. D., and Currie, G. A., Nature, 218, 1254 (1968).
Currie, G. A., and Bagshawe, K. D., Brit. J. Cancer, 23, 141 (1969).
Lindenmann, J., and Klein, P. A., Recent Results in Cancer Research, 9, 66 (Springer, New York, 1967).
Siskind, G. W., Paul, W. E., and Benacerraf, B., J. Exp. Med., 123, 673 (1966).
Burnett, F. M., and Stone, J. D., Austral. J. Exp. Biol. Med. Sci., 25, 227 (1967).
Billingham, R. E., and Medawar, P. B., Brit. J. Exp. Biol., 28, 385 (1951).
Ray, P. K., Gewurz, H., and Simmons, R. L., Fed. Proc., 29, 573 (1970).
Sanford, B. H., and Codington, J. F., J. Nat. Cancer Inst. (in the press).
Smithers, S. R., Sixth Symp. Brit. Soc. Parasitology, 55 (Blackwell, Oxford, 1968).
Simmons, R. L., Rios, A., and Ray, P. K., Surg. Forum, 21, 265 (1970).
Woodruff, J. J., and Gesner, B. M., J. Exp. Med., 129, 551 (1969).
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SIMMONS, R., RIOS, A. & RAY, P. Immunogenicity and Antigenicity of Lymphoid Cells treated with Neuraminidase. Nature New Biology 231, 179–181 (1971). https://doi.org/10.1038/newbio231179a0
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DOI: https://doi.org/10.1038/newbio231179a0
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