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Immunogenicity and Antigenicity of Lymphoid Cells treated with Neuraminidase

Abstract

SIALIC acid residues are the principal constituents on the surface of plasma membranes1 and make the chief contribution to the negative charge of the cell surface2. A number of functional alterations of the cell can be induced by removal of the sialic acid from the surface membrane by neuraminidase3–6.

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SIMMONS, R., RIOS, A. & RAY, P. Immunogenicity and Antigenicity of Lymphoid Cells treated with Neuraminidase. Nature New Biology 231, 179–181 (1971). https://doi.org/10.1038/newbio231179a0

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