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Does peritoneal dialysate affect body composition assessments using multi-frequency bioimpedance in peritoneal dialysis patients?

European Journal of Clinical Nutrition volume 67, pages 223–225 (2013)Cite this article

Subjects

Abstract

Background/Objectives:

Multi-frequency bioelectrical impedance analysis (MFBIA) is increasingly being used to assess peritoneal dialysis patients. Protein energy wasting (PEW) is a recognised complication of peritoneal dialysis. Although MFBIA can be used to assess body composition, measurements can be affected by fluid overload, and we wished to determine whether the presence of peritoneal dialysate in the peritoneal cavity equally could affect MFBIA-derived body composition assessments.

Subjects/Methods:

Fifty consecutive adult patients had MFBIA made with 2l 22.7g/l dextrose dialysate instilled into the peritoneal cavity and then after draining out.

Results:

When full, extracellular water (ECW) and the ratio of ECW to total body water (TBW) were greater compared with when empty: 13.9±3.0l versus 13.4±3.0, and 0.393±0.01 versus 0.391±0.01, P<0.001, respectively. Segmental ECW/TBW was only different for the trunk, 0.395±0.01 full versus 0.392±0.01 empty, P<0.0001. Body composition changed with a fall in skeletal muscle mass from 26.1±6.3 to 25.2±6.1kg, P<0.001, and a smaller reduction in body fat from 19.3±8.4 to 19.1±8.0kg, P=0.0104.

Conclusion:

MFBIA measurements made in peritoneal dialysis patients with peritoneal dialysate instilled can overestimate body composition, including muscle mass, and as such potentially delay the recognition of PEW. Thus, for more accurate MFBIA in peritoneal dialysis patients, the dialysate should be drained out.

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References

  1. Wang AY . Energy intake and energy expenditure profiles in peritoneal dialysis patients. Ren Nutr 2011; 21: 31–34.

    Article  Google Scholar 

  2. Davenport A . Peritonitis remains the major clinical complication of peritoneal dialysis: the London, UK, peritonitis audit 2002-2003. Perit Dial Int 2009; 29: 297–302.

    PubMed  Google Scholar 

  3. Fan S, Sayed RH, Davenport A . Extracellular volume expansion in peritoneal dialysis patients. Int J Artif Organs 2012; 35: 338–345.

    Article  CAS  Google Scholar 

  4. Han SH, Han DS . Nutrition in patients on peritoneal dialysis. Nat Rev Nephrol 2012; 8: 163–175.

    Article  CAS  Google Scholar 

  5. Fürstenberg A, Davenport A . Comparison of multifrequency bioelectrical impedance analysis and dual-energy X-ray absorptiometry assessments in outpatient haemodialysis patients. Am J Kidney Dis 2011; 57: 123–129.

    Article  Google Scholar 

  6. Parmentier SP, Schirutschke H, Schmitt B, Schewe J, Herbrig K, Pistrosch F et al. Influence of peritoneal dialysis solution on measurements of fluid status by bioimpedance spectroscopy. Int Urol Nephrol. e-pub ahead of print 19 June 2012; PMID: 22710970.

  7. Bedogni G, Malavolti M, Severi S, Poli M, Mussi C, Fantuzzi AL et al. Accuracy of an eight-point tactile-electrode impedance method in the assessment of total body water. Eur J Clin Nutr 2002; 56: 1143–1148.

    Article  CAS  Google Scholar 

  8. Fürstenberg A, Davenport A . Assessment of body composition in peritoneal dialysis patients using bioelectrical impedance and dual-energy X-Ray absorptiometry. Am J Nephrol 2011; 33: 150–156.

    Article  Google Scholar 

  9. Booth J, Pinney J, Davenport A . The effect of vascular access modality on changes in fluid content in the arms as determined by multifrequency bioimpedance. Nephrol Dial Transplant 2011; 26: 227–231.

    Article  Google Scholar 

  10. Than N, Woodrow G, Oldroyd B, Gonzalez C, Turney JH, Brownjohn AM . Effect of peritoneal fluid on whole body and segmental multiple frequency bioelectrical impedance in patients on peritoneal dialysis. Eur J Clin Nutr 2000; 54: 450–451.

    Article  CAS  Google Scholar 

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  1. UCL Centre for Nephrology, Royal Free Hospital, University College London Medical School, London, UK

    A Davenport

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  1. A Davenport
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Correspondence to A Davenport.

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Davenport, A. Does peritoneal dialysate affect body composition assessments using multi-frequency bioimpedance in peritoneal dialysis patients?. Eur J Clin Nutr 67, 223–225 (2013). https://doi.org/10.1038/ejcn.2012.205

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