Abstract
The complete amino-acid sequences of the alpha chains of the common genetic variants of human haptoglobin confirm that the α2 chain has arisen by partial gene duplication of the Hp1 locus. A homology in sequence between a portion of the haptoglobin alpha chain sequence and a series of Bence Jones light chains suggests that the functional similarity between haptoglobin and immunoglobin G may reflect a common evolutionary origin.
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BLACK, J., DIXON, G. Amino-acid Sequence of Alpha Chains of Human Haptoglobins. Nature 218, 736–741 (1968). https://doi.org/10.1038/218736a0
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DOI: https://doi.org/10.1038/218736a0
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