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Neurotrophic Control of Contracture in Slow Muscle Fibres

Abstract

SOME frog muscles, such as the iliofibularis, contain two types of muscle fibres: the “slow” fibres, with multiple innervations by small nerve fibres and capable of producing a maintained contracture when depolarized; and the “twitch” fibres which respond normally with a transient contracture and are innervated by larger motor nerve fibres1,2. Contracture characteristics of these muscle fibres seem to be determined by the type of innervation they receive, because the iliofibularis muscle loses its prolonged contracture after its original innervation has been replaced by the nerve to the sartorius, which is a purely twitch muscle3.

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ELUL, R., MILEDI, R. & STEFANI, E. Neurotrophic Control of Contracture in Slow Muscle Fibres. Nature 217, 1274–1275 (1968). https://doi.org/10.1038/2171274a0

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