Abstract
Hydropericardium hepatitis syndrome in broiler chickens is an acute, infectious disease characterized by high mortality, excess pericardial fluid and multifocal hepatic necrosis. The aetiological agent was purified to homogeneity from infected liver tissues from field outbreaks. Electron-microscopic and serological confirmation of the virus were undertaken and the disease was reproduced experimentally in broiler chicks. The results indicated that an adenovirus, fowl adenovirus serotype 4, was alone responsible for the disease in the materials studied.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
REFERENCES
Afzal, M., Muneer, R. and Stein, G., 1991. Studies on the aetiology of hydropericardium syndrome in broilers. The Veterinary Record, 128, 591-593
Anjum, A.D., 1990. Experimental transmission of hydropericardium syndrome and protection against it in commercial broiler chickens. Avian Pathology, 19, 655-660
Anjum, A.D., Sabri, M.A. and Iqbal, Z., 1989. Hydropericarditis syndrome in broiler chickens in Pakistan. The Veterinary Record, 124, 247-248
Asrani, R.K., Gupta, V.K., Sharma, S.K., Singh, S.P. and Katoch, R.C., 1997. Hydropericardium hepatopathy syndrome in Asian poultry. The Veterinary Record, 141, 271-273
Chandra, R., Shukla, S.K., Kumar, M. and Garg, S.K. 1997. Electron microscopic demonstration of adenovirus in the hepatocytes of birds experimentally infected with hydropericardium syndrome. The Veterinary Record, 138, 70-71
Cheema, A.H., Afzal, M. and Ahmad, J., 1988. Studies on the causation of hydropericardium syndrome in Pakistan. Proceedings of the National Seminar on Hydropericardium Syndrome in Chickens in Pakistan, Rawalpindi, 41-48
Cheema, A.H., Ahmad, J. and Afzal, M., 1989. An adenovirus infection of poultry in Pakistan. Revue Scientifique et Technique de l'Office Internationales des Epizooties, 8, 789-795
Gowda, R.N.S. and Satyanarayana, M.L., 1994. Hydropericardium syndrome in poultry. Indian Journal of Veterinary Pathology, 18, 159-161
Grimes, T.M., King, D.J. and Kleven, S.H., 1975. Application of microtitre cell culture method to characterization of avian adenoviruses. Avian Diseases, 20, 299-310
Hasan, S.A., 1989. Pakistan is mystified by hydropericardium syndrome. Poultry-Misset, 5, 35-37
Jadhao, S.J., Kataria, J.M., Verma, K.C. and Sah, R.L., 1997. Serotyping of Indian isolates of fowl adenovirus recovered from IBH-HPS (Litchi disease) in chickens. Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases, 18, 33-37
Khawaja, D.A., Ahmed, S., Rauf, A.M., Zulfigar, M., Mahmood, S.M. and Hassan, M., 1988. Isolation of an adenovirus from hydropericardium syndrome in broiler chicks. Pakistan Journal of Veterinary Research, 1, 2-17
Naeem, K., Niazi, T., Malik, S.A. and Cheema, A.H., 1995. Immunosuppressive potential and pathogenicity of an avian adenovirus isolate involved in hydropericardium syndrome in broilers. Avian Diseases, 39, 723-728
Satyanarayana, M.L., 1998. Etiopathology and pathogenesis of hydropericardium syndrome in broilers, (PhD thesis, University of Agricultural Sciences, Bangalore, India)
Voss, M., Vielitz, E., Hess, M., Prusas, C.H. and Mazaherri, A., 1996. Aetiological aspects of hepatitis and HPS caused by pathogenic adenoviruses in different countries. International Symposium on Adenovirus and Reovirus Infections in Poultry, Rauischholzhausen, Germany, 75-78
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ganesh, K., Raghavan, R., Gowda, R. et al. Purification and Characterization of the Aetiological Agent of Hydropericardium Hepatitis Syndrome from Infected Liver Tissues of Broiler Chickens. Tropical Animal Health and Production 34, 7–17 (2002). https://doi.org/10.1023/A:1013777509538
Issue Date:
DOI: https://doi.org/10.1023/A:1013777509538