Abstract
Obesity is the result of a complex interplay among several factors leading to medical, functional and psychosocial consequences that markedly reduce life expectancy and impair quality of life. Is obesity itself a disease? Is obesity a brain disease? Who should treat obesity? This paper is a narrative review aimed to describe and to argue the prevalent position of some major Italian scientific and academic institutions dealing with obesity. According to the recent statements and recommendations published by the Italian Society for Obesity (SIO) and the Italian Society for the Study of Eating Disorders (SISDCA), the management of obese patients should include five main levels of care: (1) primary care, (2) outpatient treatment, (3) intensive outpatient treatment, (4) residential rehabilitative treatment, and (5) hospitalization. Ideally, patients suffering from obesity need a multidimensional evaluation intended to design an individualized treatment plan applying different procedures and therapeutic strategies (diet, physical activity and functional rehabilitation, educational therapy, cognitive-behavior therapy, drug therapy, and bariatric surgery). This thorough approach should address not only weight loss but also quality of weight loss, medical and psychiatric comorbidity, psychosocial problems, and physical disability. Such management of obesity requires an effective multiprofessional team, while health services have to overcome a number of administrative and organizational barriers that do not account for diseases requiring resources and professionals from different areas of medicine. Integrating several competences in a team-based approach demands specific education, skills and expertise. As for other diseases, the principles of complexity theory may offer a model useful to implement both teamwork and care delivery for patients with obesity.
Similar content being viewed by others
References
Mechanick JI, Garber AJ, Handelsman Y, Garvey WT (2012) American Association of Clinical Endocrinologists’ position statement on obesity and obesity medicine. Endocr Pract 18(5):642–648
Apovian CM (2012) Obesity medicine: a new specialty in medicine or a focus in endocrinology? Nutrition is the real subspecialty in medicine. Endocr Pract 18(5):649–650
Donini LM (2013) Debate on obesity medicine. Endocr Pract 19(1):169
Donini LM, Cuzzolaro M, Spera G et al (2010) Obesity and eating disorders. Indications for the different levels of care. An Italian expert consensus document. Eat Weight Disord 15(1–2 Suppl):1–31
Greenberg JA (2013) Obesity and early mortality in the United States. Obesity (Silver Spring) 21(2):405–412
Childers DK, Allison DB (2010) The ‘obesity paradox’: a parsimonious explanation for relations among obesity, mortality rate and aging? Int J Obes (Lond) 34(8):1231–1238
Masters RK, Powers D, Link BG (2013) Obesity and US mortality risk over the adult life course. Am J Epidemiol 177(5):431–442
Donini LM, Savina C, Gennaro E et al (2012) A systematic review of the literature concerning the relationship between obesity and mortality in the elderly. J Nutr Health Aging 16(1):89–98
Hinnouho GM, Czernichow S, Dugravot A, Batty GD, Kivimaki M, Singh-Manoux A (2013) Metabolically healthy obesity and risk of mortality: does the definition of metabolic health matter? Diabetes Care 36(8):2294–2300
Bray GA (2004) Medical consequences of obesity. J Clin Endocrinol Metab 89(6):2583–2589
Donini LM, Poggiogalle E, Del Balzo V et al (2013) How to estimate fat mass in overweight and obese subjects. Int J Endocrinol 2013:285680
Lee YS (2009) Consequences of childhood obesity. Ann Acad Med Singap 38(1):75–77
Pulgaron ER (2013) Childhood obesity: a review of increased risk for physical and psychological comorbidities. Clin Ther 35(1):A18–A32
Morandi A, Maschio M, Marigliano M et al (2013) Screening for impaired glucose tolerance in obese children and adolescents: a validation and implementation study. Pediatr Obes. doi:10.1111/j.2047-6310.2012.00136.x (Epub ahead of print)
Donini LM, Brunani A, Sirtori A et al (2011) Assessing disability in morbidly obese individuals: the Italian Society of Obesity test for obesity-related disabilities. Disabil Rehabil 33(25–26):2509–2518
Capodaglio P, Faintuch J et al (eds) (2013) Disabling obesity. From determinants to health care models. Springer, New York
Donini LM, Savina C, Cannella C et al (2009) Multidisciplinary approach to obesity. Eat Weight Disord 14(1):23–32
Anderson WL, Wiener JM, Khatutsky G, Armour BS (2013) Obesity and people with disabilities: the implications for health care expenditures. Obesity 21(12):E798–E804. doi:10.1002/oby.20531
Capodaglio P, Cimolin V, Tacchini E, Precilios H, Brunani A (2013) Effectiveness of in-patient rehabilitation in obesity-related orthopedic conditions. J Endocrinol Invest (Epub ahead of print)
Medical Society of the State of New York (2004) Resolution 421 AMA Annual Meeting. Available at: http://www.amaassn.org/meetings/public/annual04/421a04.doc
Allison DB, Downey M et al (2008) Obesity as a disease: a white paper on evidence and arguments commissioned by the Council of the Obesity Society. Obesity (Silver Spring) 16(6):1161–1177
American Association of Clinical Endocrinologists (AACE) (2011) (2011, Published on AACE Online Newsroom (http://media.aace.com) on 7/29/11 9:23 am). “American Association of Clinical Endocrinologists (AACE) Declares Obesity a Disease State.”
American Medical Association House of Delegates (2013) Resolution 420 (A-13)
Capodaglio P, Liuzzi A (2013) Obesity: a disabling disease or a condition favoring disability? Eur J Phys Rehabil Med 49(3):395–398
Heshka S, Allison DB (2001) Is obesity a disease? Int J Obes Relat Metab Disord 25(10):1401–1404
Cuzzolaro M (2013) Obesity. Psychiatric aspects. Disabling obesity. From determinants to health care models. In: Capodaglio P, Faintuch J, Liuzzi A, Springer, New York, pp 183-197
Ahima RS, Lazar MA (2013) The health risk of obesity—better metrics imperative. Science 341(6148):856–858
Blackburn GL (2011) Medicalizing obesity: individual, economic, and medical consequences. Virtual Mentor 13(12):890–895
Volkow ND, O’Brien CP (2007) Issues for DSM-V: should obesity be included as a brain disorder? Am J Psychiatry 164(5):708–710
Volkow ND, Wang GJ, Tomasi D, Baler RD (2013) Obesity and addiction: neurobiological overlaps. Obes Rev 14(1):2–18
American Psychiatric Association (2013) Diagnostic and Statistical Manual of Mental Disorders, DSM-5, 5th edn. American Psychiatric Publishing, Arlington
Petry NM, Barry D, Pietrzak RH, Wagner JA (2008) Overweight and obesity are associated with psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Psychosom Med 70(3):288–297
Simon GE, Von Korff M, Saunders K et al (2006) Association between obesity and psychiatric disorders in the US adult population. Arch Gen Psychiatry 63(7):824–830
Dent R, Blackmore A, Peterson J et al (2012) Changes in body weight and psychotropic drugs: a systematic synthesis of the literature. PLoS One 7(6):e36889
Nihalani N, Schwartz TL, Siddiqui UA, Megna JL (2012) Obesity and psychotropics. CNS Neurosci Ther 18(1):57–63
Anton SD, Newton RL Jr, Sothern M, Martin CK, Stewart TM, Williamson DA (2006) Association of depression with body mass index, sedentary behavior, and maladaptive eating attitudes and behaviors in 11 to 13-year old children. Eat Weight Disord 11(3):e102–e108
Adamus-Leach HJ, Wilson PL, O’Connor DP, Rhode PC, Mama SK, Lee RE (2013) Depression, stress and body fat are associated with binge eating in a community sample of African American and Hispanic women. Eat Weight Disord 18(2):221–227
Benson LP, Williams RJ, Novick MB (2013) Pediatric obesity and depression: a cross-sectional analysis of absolute BMI as it relates to children’s depression index scores in obese 7- to 17-year-old children. Clin Pediatr (Phila) 52(1):24–29
Pan A, Sun Q, Czernichow S et al (2012) Bidirectional association between depression and obesity in middle-aged and older women. Int J Obes (Lond) 36(4):595–602
Cuzzolaro, M, Vetrone G (2009) Overview of evidence on the underpinnings of binge eating disorder and obesity. Evidence based treatments for eating disorders: children, adolescents and adults. In: Dancyger I, Fornari V, Nova Science Publishers, New York, pp 53–70
Gronning I, Scambler G, Tjora A (2013) From fatness to badness: the modern morality of obesity. Health 17(3):266–283
Puhl R, Brownell KD (2001) Bias, discrimination, and obesity. Obes Res 9(12):788–805
Puhl RM, Masheb RM, White MA, Grilo CM (2010) Attitudes toward obesity in obese persons: a matched comparison of obese women with and without binge eating. Eat Weight Disord 15(3):e173–e179
Sbraccia P, Vettor R (2012) SIO, Società Italiana dell’Obesità e ADI, Associazione Dietetica Italiana. Standard italiani per la cura dell’obesità 2012–2013. SIO, Società Italiana dell’Obesità, Roma
Expert Panel on the Identification, Evaluation, and Treatment of Overweight in Adults (1998) Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: executive summary. Am J Clin Nutr 68(4):899–917
Dalle Grave R, Calugi S, El Ghoch M (2013) Lifestyle modification in the management of obesity: achievements and challenges. Eat Weight Disord (Epub ahead of print)
Wing RR, Bolin P, Brancati FL, Look AHEAD Research Group et al (2013) Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med 369(2):145–154
Sjostrom L, Lindroos AK, Peltonen M et al (2004) Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med 351(26):2683–2693
Fairburn CG (2008) Cognitive behavior therapy and eating disorders. Guilford Press, New York
Wilson GT, Wilfley DE, Agras WS, Bryson SW (2010) Psychological treatments of binge eating disorder. Arch Gen Psychiatry 67(1):94–101
Dalle Grave R (2011) Intensive cognitive behavioural treatment for eating disorders. Eur Psychiatric Rev 4(1):59–64
Dalle Grave R, Calugi S, Gavasso I, El Ghoch M, Marchesini G A (2013) randomized trial of energy-restricted high-protein versus high-carbohydrate, low-fat diet in morbid obesity. Obesity 21(9):1774–1781. doi:10.1002/oby.20320
Wadden TA, McGuckin BG, Rothman RA, Sargent SL (2003) Lifestyle modification in the management of obesity. J Gastrointest Surg 7(4):452–463
Capodaglio P, La Fortuna C, Petroni ML et al (2013) Rationale for hospital-based rehabilitation in obesity with comorbidities. Eur J Phys Rehab Med 49:399–417
Upshur R, Tracy S (2008) Chronicity and complexity. Is what’s good for the diseases always good for the patients? Can Fam Physician 54:1655–1658
Stans S, Stevens J, Beurskens A (2013) Interprofessional practice in primary care: development of a tailored process model. J Multidisc Healthc 6:139–147
Puhl R, Wharton C, Heuer C (2009) Weight bias among dietetics students: implications for treatment practices. J Am Diet Assoc 109:438–444
Scottish Intercollegiate Guidelines Network (2010) Management of Obesity: a national Clinical Guideline by the Scottish Intercollegiate Guideline Network, Edinburgh
Loveman E, Frampton GK, Shepherd J et al (2011) The clinical effectiveness and costeffectiveness of long-term weight management schemes for adults: a systematic review. Health Technol Assess 15(2):1–182. doi:10.3310/hta15020
Romanova M, Liang L, Deng ML, Li Z, Heber D (2013) Effectiveness of the MOVE! Multidisciplinary weight loss program for veterans in Los Angeles. Prev Chronic Dis 10:120325. doi:10.5888/pcd10.120325
Hainer V, Toplak H, Mitrakou A (2008) Treatment modalities of obesity what fits whom. Diabet Care 31(Suppl. 2):S269–S277
Prentice AM, Jebb SA (2001) Beyond body mass index. Obes Rev 2:141–147
Pories WJ, Dohm LG, Mansfield CJ (2010) Beyond the BMI: the Search for Better Guidelines for Bariatric Surgery. Obesity 18:865–871. doi:10.1038/oby.2010.8
Auyeung TW, Lee TSW, Leung J, Kwok T, Woo J Adiposity to muscle ratio predicts incident physical limitation in a cohort of 3,153 older adults—an alternative measurement of sarcopenia and sarcopenic obesity. Age 35(4):1377–1385. doi:10.1007/s11357-012-9423-9
De Lorenzo A, Del Gobbo V, Premrov MG, Bigioni M, Galvano F, Di Renzo L (2007) Normal-weight obese syndrome: early inflammation? Am J Clin Nutr 85:40–45
Hafekost K, Lawrence D, Mitrou F, O’Sullivan TA, Zubrick SR (2013) Tackling overweight and obesity: does the public health message match the science? BMC Med 11:41
Glouberman S, Zimmerman B (2002) Complicated and complex systems: what would successful reform of medicare look like? Commission on the future of health care in Canada. Discussion paper
Barach P, Johnson JK (2006) Understanding the complexity of redesigning care around the clinical system. Qual Saf Health Care 15:i10–i16
Lipsitz LA (2012) Understanding health care as a complex system. JAMA 308(3):243–244
Aronne LJ, Nelinson DS, Lillo JL (2009) Obesity as a disease state: a new paradigm for diagnosis and treatment. Clinical Cornerstone 9(4):9–29
Hammond RA (2009) Complex systems modeling for obesity research. Prev Chronic Dis 6(3):A97
Plsek PE, Wilson T (2001) Complexity, leadership, and management in healthcare organizations. BMJ 323:746–749
Martin CM, Sturmberg JP (2005) General practice—chaos, complexity and innovation. MJA 183:106–109
Conflict of interest
The authors declare that they have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Donini, L.M., Grave, R.D., Caretto, A. et al. From simplicity towards complexity: the Italian multidimensional approach to obesity. Eat Weight Disord 19, 387–394 (2014). https://doi.org/10.1007/s40519-013-0097-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s40519-013-0097-9