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Distal renal tubular acidosis

An uncommon cause of enamel hypoplasia in siblings

  • case study
  • Published:
international journal of stomatology & occlusion medicine

Abstract

The kidneys are vital organs for maintaining homeostasis and have two important roles in maintaining the acid-base balance: to reabsorb bicarbonate from and to excrete hydrogen ions into urine. Renal tubular acidosis (RTA) is a form of metabolic acidosis that arises from a lack of urine excretion of H+ ions or loss of bicarbonate (\(\text{HCO}_{3}^{-}\)) ions due to a variety of renal tubular disorders. Acid-base disturbances can result in changes in dental health and in the development and the structure of the teeth. This article describes, to the best of the authors’ knowledge, the first case report of dental abnormalities occurring in two siblings with distal RTA.

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References

  1. Brewer DE. Disorders of acid-base balance. Pediatr Clin North Am. 1990;37:429–47.

    PubMed  CAS  Google Scholar 

  2. Winsnes A, Monn E, Stokke O, Feyling T. Congenital persistent proximal type renal tubular acidosis in two brothers. Acta Pedatr Scand. 1979;68:861–8.

    Article  CAS  Google Scholar 

  3. Koppang HS, Stene T, Solheim T, Larheim TA, Wisnes A, Monn E, et al. Dental features in congenital persistent renal tubular acidosis of proximal type. Scand J Dent Res. 1984;92:489–95.

    PubMed  CAS  Google Scholar 

  4. Soriano JR. Renal tubular acidosis, the clinical entity. J Am Soc Nephrol. 2002;13:2160–70.

    Article  Google Scholar 

  5. Dunger DB, Brenton DP, Cain AR. Renal tubular acidosis and nerve deafness. Arch Dis Child. 1980;55:221–5.

    Article  PubMed  CAS  Google Scholar 

  6. Backman T, Pajari U, Larmas M. Effect of metabolic acidosis on dentinogenesis in rat. In: Shimano M, Maeda T, Suda H, Takahashi K, editors. Dentin pulp complex. Tokyo: Quintessence; 1999. pp. 291–2.

    Google Scholar 

  7. Koch MJ, Buhrer R, Pioch T, Schrarer K. Enamel hypoplasia of primary teeth in chronic renal failure. Pediatr Nephrol. 1999;13:68–72.

    Article  PubMed  CAS  Google Scholar 

  8. Whitford GM, Pashley DH. Fluoride absorption: the influence of gastric acidity. Calcif Tissue Int. 1984;36:302–7.

    Article  PubMed  CAS  Google Scholar 

  9. Angmar-Mansson B, Whitford GM. Effects of acid-base status and fluoride on developing canine enamel (abstract). Caries Res. 1986;20:159.

    Google Scholar 

  10. Woodhead JC, Nowak AJ, Crall JJ, Robillard JE. Dental abnormalities in children with chronic renal failure. Pediatr Dent. 1982;4:281–5.

    Google Scholar 

  11. Jaffe EC, Roberts J, Chantker C, Carter JE. Dental findings in chronic renal failure. Br Dent J. 1986;160:18–20.

    Article  PubMed  CAS  Google Scholar 

  12. Bender IB, Naidorf IJ. Dental observations in vitamin D-resistant rickets with special reference to periapical lesions. J Endod. 1985;11:514–20.

    Article  PubMed  CAS  Google Scholar 

  13. Ganibegovic M. Dental radiographic changes in chronic renal failure. Med Arch. 2000;54:115–8.

    CAS  Google Scholar 

  14. Zambrano M, Nikitakis G, Sanchez-Queved MC, Saukk JJ, Sedano H, Rivera H. Oral and dental manifestations of vitamin D-resistant rickets type 1: report of a pediatric case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95(6):705–9.

    Article  PubMed  Google Scholar 

  15. Sampathkumar K, Sah A, Seralathan G. Dental caries in renal tubular acidosis. Kidney Int. 2011;801:248.

    Google Scholar 

  16. Bahadure RN, Thosar N, Kriplani R, Baliga S, Fulzele P. Dental aspect of distal tubular renal acidosis with genu valgum secondary to rickets: a case report. Case Rep Dent. 2012; doi:10.1155/2012/374945.

  17. Procter R, Kumar N, Stein A, Moles D, Porter S. Oral and dental aspects of chronic renal failure. J Dent Res. 2005;84:199–208.

    Article  Google Scholar 

  18. Al-Nowaiser A, Roberts GJ, Trompter RS, Wilson M, Lucas VS. Oral health in children with chronic renal failure. Pediatr Nephrol. 2003;18:39–45.

    Article  Google Scholar 

  19. Jain M, Agarwal MP, Wasir JS, Dwivedi S. Amelogenesis imperfecta and distal renal tubular acidosis presenting as hypokalemic periodic paralysis. J Assoc Physicians India. 1999;47(12):1205–6.

    CAS  Google Scholar 

  20. Seow WK. The effect of medical therapy on dentin formation in vitamin D-resistant rickets. Pediatr Dent. 1991;13(2):97–102.

    PubMed  CAS  Google Scholar 

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Conflict of interest

The authors declare that there is no actual or potential conflict of interest in relation to this article.

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Authors and Affiliations

  1. 74, 4th Cross, Thanthai Periyar Nagar, 605005, Pondicherry, India

    Balasubramanian Krishnan MDS, DNB, MOMS RCPS (Glasgow)

  2. Department of Dentistry, Jawarharlal Institute of Postgraduate Medical Education & Research (JIPMER), 605006, Pondicherry, India

    Balasubramanian Krishnan MDS, DNB, MOMS RCPS (Glasgow)

  3. Department of Pediatrics, Jawarharlal Institute of Postgraduate Medical Education & Research (JIPMER), 605006, Pondicherry, India

    Sriram Krishnamurthy M.D.

  4. Department of Oral Medicine & Radiology, Mahatma Gandhi Postgraduate Institute of Dental Sciences (MGPGI), 605006, Pondicherry, India

    M. Jonathan Daniel MDS

Authors
  1. Balasubramanian Krishnan MDS, DNB, MOMS RCPS (Glasgow)
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  2. Sriram Krishnamurthy M.D.
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  3. M. Jonathan Daniel MDS
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Corresponding author

Correspondence to Balasubramanian Krishnan MDS, DNB, MOMS RCPS (Glasgow).

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Krishnan, B., Krishnamurthy, S. & Daniel, M. Distal renal tubular acidosis. J. Stomat. Occ. Med. 5, 183–187 (2012). https://doi.org/10.1007/s12548-012-0061-8

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  • DOI: https://doi.org/10.1007/s12548-012-0061-8

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