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Complete nucleotide sequence of a mumps virus SP strain isolated in China

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Virologica Sinica

Abstract

The complete nucleotide sequence of the mumps virus SP, which was isolated in China, was determined. As with other mumps viruses, its genome was 15 384 nucleotides (nts) in length and encoded seven proteins. The full-length nucleotide sequence of the SP isolate differed from other strains by 4%–6.8% at the nucleotide sequence level. Due to variations of amino acids over the full genome (including the HN and N genes), this isolate exhibited significant variations in the antigenic sites. This report is the first to describe the full-length genome of a genotype F strain and provide an overview of the diversity of genetic characteristics of a circulating mumps virus.

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Authors and Affiliations

  1. Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, 650118, China

    Shao-hui Ma, Jian-sheng Liu, Hai-jing Shi, Li-chun Wang, Jing-jing Wang, Long-ding Liu & Qi-han Li

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  1. Shao-hui Ma
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  2. Jian-sheng Liu
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  3. Hai-jing Shi
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  4. Li-chun Wang
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  5. Jing-jing Wang
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  6. Long-ding Liu
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  7. Qi-han Li
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Correspondence to Qi-han Li.

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Foundation iterms: Public Benefit Grant of Ministry of Health, China (200802035); Natural Science Foundation of Yunnan province (2008CD153)

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Ma, Sh., Liu, Js., Shi, Hj. et al. Complete nucleotide sequence of a mumps virus SP strain isolated in China. Virol. Sin. 24, 28–36 (2009). https://doi.org/10.1007/s12250-009-2984-9

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  • DOI: https://doi.org/10.1007/s12250-009-2984-9

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