Abstract
We aimed to investigate the correlation between the Glasgow Coma Scale (GCS), the injury severity score (ISS) and serum levels of trace elements (TE) in severe trauma patients to analyze alteration of the levels of trace elements and serum biochemical indexes in the period of admission from 126 adult cases of severe brain trauma with traffic accidents. Multi-trace elements for patients in the trauma-TE groups were used. The results indicated that all patients presented an acute trace elements deficiency syndrome (ATEDs) after severe trauma, and the correlation between ISS and serum levels of Fe, Zn, and Mg was significant. Compared to the normal control group, levels of the trace elements in serum were significantly decreased after trauma, suggesting that enhancement of immunity to infection and multiple organ failure (MOF) via the monitoring and supplement of trace elements will be a good strategy to severe traumatic patients in clinics.
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Acknowledgments
We are grateful to Miss Xingxing Wang and Mr. Bo Li for the data analysis. We appreciate the support from the Zhejiang Provincial Natural Science Foundation (LQ14H230001), Scientific Research Fund of Zhejiang Provincial Education Department (Y201330031), and the National Natural Science Foundation Council of China (30772458, 81400489, and 81400654).
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The authors declare no conflict of interest.
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Guangtao Xu and Bo Hu contributed equally to this work.
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Xu, G., Hu, B., Chen, G. et al. Analysis of Blood Trace Elements and Biochemical Indexes Levels in Severe Craniocerebral Trauma Adults with Glasgow Coma Scale and Injury Severity Score. Biol Trace Elem Res 164, 192–197 (2015). https://doi.org/10.1007/s12011-014-0225-z
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DOI: https://doi.org/10.1007/s12011-014-0225-z