Abstract
Background
Mood disorders are common among patients seeking bariatric surgery although little data exist regarding the prevalence of bipolar symptoms in this population and how they influence surgical outcomes. Our aim was to describe baseline rates of bipolar symptoms and their relationship to psychological factors and completing surgery in a sample of adults seeking bariatric surgery at an academic medical center.
Methods
We retrospectively reviewed the relationship of bipolar symptoms to demographic characteristics, baseline weight, psychological factors, and bariatric surgery completion.
Results
Nine hundred thirty-five patients completed the preoperative psychological evaluation. Six percent of the preoperative sample screened positive for symptoms of bipolar disorder. Patients with bipolar symptoms endorsed more robust psychopathology, trauma history, and problematic eating behaviors than patients without bipolar symptoms. Twenty-two percent of the patients with bipolar symptoms underwent bariatric surgery (n = 12), yet only 13 % were denied bariatric surgery for psychiatric reasons, suggesting that other variables may influence the completion of bariatric surgery for these patients.
Conclusion
Prevalence rates of bipolar symptoms may be greater in patients seeking bariatric surgery compared with the general population, and few patients with bipolar symptoms actually undergo bariatric surgery. Psychological factors differentiate patients with bipolar symptoms who undergo bariatric surgery vs those who do not.
Similar content being viewed by others
References
Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292:1724–37.
Adams TD, Davidson LE, Litwin SE, et al. Health benefits of gastric bypass surgery after 6 years. JAMA. 2012;308:1122–31.
Goldstein BI, Liu SM, Zivkovic N, et al. The burden of obesity among adults with bipolar disorder in the United States. Bipolar Disord. 2011;4:387–95.
McElroy SL, Frye MA, Suppes T, et al. Correlates of overweight and obesity in 644 patients with bipolar disorder. J Clin Psychiatry. 2002;63:207–13 [Multicenter Study Research Support, Non-U.S. Gov’t].
McElroy SL, Keck PL. Obesity in bipolar disorder: an overview. Curr Psych Rep. 2012;14:650–8.
McIntyre RS, Soczynska JK, Beyer JL, et al. Medical comorbidity in bipolar disorder: reprioritizing unmet needs. Curr Opin Psychiatr. 2007;20:406–16.
McElroy SL, Kotwal R, Keck Jr PE, et al. Comorbidity of bipolar and eating disorders: distinct or related disorders with shared dysregulations? J Affect Disord. 2005;86:107–27.
McElroy SL, Frye MA, Hellemann G, et al. Prevalence and correlates of eating disorders in 875 patients with bipolar disorder. J Affect Disord. 2011;128:191–8 [Research Support, Non-U.S. Gov’t].
Calkin C, van de Velde C, Ruzickova M, et al. Can body mass index help predict outcome in patients with bipolar disorder? Bipolar Disord. 2009;11:650–6.
Kalarchian MA, Marcus MD, Levine MD, et al. Psychiatric disorders among bariatric surgery candidates: relationship to obesity and functional health status. Am J Psychiatry. 2007;164:328–34.
Mauri M, Rucci P, Calderone A, et al. Axis I and II disorders and quality of life in bariatric surgery candidates. J Clin Psychiatry. 2008;69:295–301.
Muhlhans B, Horbach T, de Zwaan M. Psychiatric disorders in bariatric surgery candidates: a review of the literature and results of a German prebariatric surgery sample. Gen Hosp Psychiatry. 2009;31:414–21.
Kessler Rc MKAZS et al. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States: results from the national comorbidity survey. Arch Gen Psychiatry. 1994;51:8–9.
Angst J, Gamma A, Benazzi F, et al. Toward a re-definition of subthreshold bipolarity: epidemiology and proposed criteria for bipolar two, minor BD and hypomania. J Affect Disord. 2003;73:133–46.
Alciati A, D’Ambrosio A, Foschi D, et al. Bipolar spectrum disorders in severely obese patients seeking surgical treatment. J Affect Disord. 2007;101:131–8.
Alciati A, Gesuele F, Rizzi A, et al. Childhood parental loss and bipolar spectrum in obese bariatric surgery candidates. Int J Psychiatry Med. 2011;41:155–71 [Research Support, Non-U.S. Gov’t].
Walfish S, Vance D, Fabricatore AN. Psychological evaluation of bariatric surgery applicants: procedures and reasons for delay or denial of surgery. Obes Surg. 2007;17:1578–83.
Bauchowitz AU, Gonder-Frederick LA, Olbrisch ME, et al. Psychosocial evaluation of bariatric surgery candidates: a survey of present practices. Psychosom Med. 2005;67:825–32.
Steinmann WC, Suttmoeller K, Chitima-Matsiga R, et al. Bariatric surgery: 1-year weight loss outcomes in patients with bipolar and other psychiatric disorders. Obes Surg. 2011;21:1323–9.
Semanscin-Doerr DA, Windover A, Ashton K, et al. Mood disorders in laparoscopic sleeve gastrectomy patients: does it affect early weight loss? Surg Obes Relat Dis. 2010;6:191–6.
Ahmed AT, Warton EM, Schaefer CA, et al. The effect of bariatric surgery on psychiatric course among patients with bipolar disorder. Bipolar Disord. 2013;15:753–63.
Hirschfeld RM, Williams JB, Spitzer RL, et al. Development and validation of a screening instrument for bipolar spectrum disorder: the mood disorder questionnaire. Am J Psychiatry. 2000;157:1873–5 [Research Support, Non-U.S. Gov’t].
Hirschfeld RMA, Holzer C, Calabrese JR, et al. Validity of the mood disorder questionnaire: a general population study. Am J Psychiatry. 2003;160:178–80 [Research Support, Non-U.S. Gov’t Validation Studies].
Beck AT, Steer RA, Brown GK. Beck depression inventory: manual. 2nd ed. 2nd ed: Boston7 Harcourt, Brace and Company; 1996.
Spitzer RL, Kroenke K, Williams JBW, et al. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166:1092–7 [Comparative Study Multicenter Study Research Support, Non-U.S. Gov’t].
Babor TF, Higgins-Biddle J. AUDIT, the alcohol use disorders identification test: guidelines for use in primary care. 2nd ed. Geneva: World Health Organization; 2001.
King Wc CJMJE et al. Prevalence of alcohol use disorders before and after bariatric surgery. JAMA. 2012;307:2516–25.
Masheb RM, Grilo CM. Emotional overeating and its associations with eating disorder psychopathology among overweight patients with binge eating disorder. Int J Eat Disord. 2006;39:141–6.
Bernstein DP, Fink L, Handelsman L, et al. Initial reliability and validity of a new retrospective measure of child abuse and neglect. Am J Psychiatry. 1994;151:1132–6.
Simons J, Gaher R. The distress tolerance scale: development and validation of a self-report measure. Motiv Emot. 2005;29:83–102.
Clark MM, Abrams DB, Niaura RS, et al. Self-efficacy in weight management. J Consult Clin Psychol. 1991;59:739–44.
Heinberg LJ. The role of psychological testing for bariatric/metabolic surgery candidates. Bariatric Times [Internet] 2013 February; Available from: http://bariatrictimes.com/the-role-of-psychological-testing-for-bariatricmetabolic-surgery-candidates/.
Batsis JA, Clark MM, Grothe K, et al. Self-efficacy after bariatric surgery for obesity. A population-based cohort study. Appetite. 2009;52(3):637–45.
Hrabosky JI, White MA, Masheb RM, et al. Psychometric evaluation of the eating disorder examination-questionnaire for bariatric surgery candidates. Obesity. 2008;16:763–9.
Frye MA. Clinical practice. Bipolar disorder: a focus on depression. N Engl J Med. 2011;364:51–9.
Strakowski SM, Fleck DE, Maj M. Broadening the diagnosis of bipolar disorder: benefits vs. risks. World Psych. 2011;10:181–6.
Judd LL, Akiskal HS. The prevalence and disability of bipolar spectrum disorders in the US population: re-analysis of the ECA database taking into account subthreshold cases. J Affect Disord. 2003;73:123–31.
Dickerson FB, Boronow JJ, Stallings CR, et al. Association between cognitive functioning and employment status of persons with bipolar disorder. Psychiatr Serv. 2004;55:54–8.
Zimmerman M, Galione JN, Ruggero CJ, et al. Are screening scales for bipolar disorder good enough to be used in clinical practice? Compr Psychiatry. 2011;52:600–6.
Ahmed A, Blair TW, McIntyre R. Surgical treatment of morbid obesity among patients with bipolar disorder: a research agenda. Adv Ther. 2011;28:389–400.
Conflict of interest
Drs. Grothe, Mundi, Himes, Sarr, and Clark; Ms. Geske; and Ms. Kalsy declare that they have no conflicts of interest. Dr. Frye discloses that he receives grant support from Myriad and Pfizer. He discloses nonfinancial support from GlaxoSmithKline, Astra Zeneca, Bristol-Myers-Squib, Otsuka, and Sanofi-Aventis. These relationships have had no influence on the material in this paper.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Grothe, K.B., Mundi, M.S., Himes, S.M. et al. Bipolar Disorder Symptoms in Patients Seeking Bariatric Surgery. OBES SURG 24, 1909–1914 (2014). https://doi.org/10.1007/s11695-014-1262-6
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11695-014-1262-6