Combined kidney-pancreas transplantation is the treatment of choice for end-stage diabetic nephropathy. Weight gain post-transplant increases the risk for post-transplant complications and death due to cardiovascular events. Gastric pacemakers have been used for therapy of diabetic gastropathy and for the treatment of moderate morbid obesity. We report a patient who experienced significant weight gain following successful kidney-pancreas transplantation and was thereafter successfully treated for diabetic gastroparesis and morbid obesity by use of a laparoscopically implanted gastric pacemaker.
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References
Sutherland DE, Gruessner RW, Dunn DL. Lessons learned from more than 1,000 pancreas transplants at a single institution. Ann Surg 2001; 233: 463–501.
Bumgardner GL, Henry ML, Elkhammas E et al. Obesity as a risk factor after combined pancreas/kidney transplantation. Transplantation 1995; 60: 1426–30.
McCallum RW, Brown RL. Diabetic and nondiabetic gastroparesis. Curr Treat Options Gastroenterol 1998; 1: 1–7.
Forster J, Sarosiek I, Delcore R et al. Gastric pacing is a new surgical treatment for gastroparesis. Am J Surg 2001; 182: 676–81.
Shikora SA. “What are the yanks doing?” the U.S. experience with implantable gastric stimulation (IGS) for the treatment of obesity - update on the ongoing clinical trials. Obes Surg 2004; 14 (Suppl 1): S40–S48.
Miller KA. Implantable electrical gastric stimulation to treat morbid obesity in the human: operative technique. Obes Surg 2002; 12 (Suppl 1): 17S–20S.
Weiss H, Nehoda H, Labeck B et al. Organ transplantation and obesity: evaluation, risks and benefits of therapeutic strategies. Obes Surg 2000; 10: 465–9.
Alexander JW, Goodman HR, Gersin K et al. Gastric bypass in morbidly obese patients with chronic renal failure and kidney transplant. Transplantation 2004; 78: 469–74.
Humar A, Ramcharan T, Kandaswamy R et al. Technical failures after pancreas transplants: why grafts fail and the risk factors — a multivariate analysis. Transplantation 2004; 78: 1188–92.
Jones JW Jr, Mizrahi SS, Bentley FR. Type II diabetes after combined kidney and pancreas transplantation for type I diabetes mellitus and end-stage renal disease. Clin Transplant 1996; 10 (6 Pt 1): 574–5.
Parkman HP, Hasler WL, Fisher RS. American Gastroenterological Association technical review on the diagnosis and treatment of gastroparesis. Gastroenterology 2004; 127: 1592–622.
Forster J, Sarosiek I, Lin Z et al. Further experience with gastric stimulation to treat drug refractory gastroparesis. Am J Surg 2003; 186: 690–5.
Lin Z, Forster J, Sarosiek I et al. Treatment of diabetic gastroparesis by high-frequency gastric electrical stimulation. Diabetes Care 2004; 27: 1071–6.
Chen J. Mechanisms of action of the implantable gastric stimulator for obesity. Obes Surg 2004; 14 (Suppl 1): S28–32.
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Bonatti, H., Brandacher, G., Hoeller, E. et al. Laparoscopically Implanted Gastric Pacemaker after Kidney-Pancreas Transplantation: Treatment of Morbid Obesity and Diabetic Gastroparesis. OBES SURG 17, 100–103 (2007). https://doi.org/10.1007/s11695-007-9013-6
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DOI: https://doi.org/10.1007/s11695-007-9013-6