Skip to main content
Log in

Haplotype data of 23 Y-chromosome markers in Minnan Han Chinese and comparison with those of 12 Y-chromosome markers

  • Published:
Journal of Huazhong University of Science and Technology [Medical Sciences] Aims and scope Submit manuscript

Summary

We genotyped 23 Y-STR loci (DYS576, DYS389I, DYS448, DYS389II, DYS19, DYS391, DYS481, DYS549, DYS533, DYS438, DYS437, DYS570, DYS635, DYS390, DYS439, DYS392, DYS643, DYS393, DYS458, DYS385a/b, DYS456, and GATA-H4) in a sample of 109 unrelated male Chinese people residing in Minnan area and compared the results with those from our previous study on 12 Y-STR. The haplotype diversity and the discrimination capacity of the 23 Y-STR reached 0.9903 and 0.9725, respectively, and the genetic diversity for each locus ranged from 0.321 (DYS391) to 0.955 (DYS385). Besides, we observed a strong correlation between the number of Y-STR markers and the substantial improvement of forensic parameters used to discriminate between individuals. The results indicated that these highly polymorphic Y-STR markers were useful for human identification in forensic cases and paternity tests within the Minnan Han Chinese population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. De Knijff P, Kayser M, Caglià A, et al. Chromosome Y microsatellites: population genetic and evolutionary aspects. Int J Legal Med, 1997,110(3):134–140

    Article  PubMed  Google Scholar 

  2. Kwak KD, Jin HJ, Shin DJ, et al. Y-chromosomal STR haplotypes and their applications to forensic and population studies in east Asia. Int J Legal Med, 2005,119(4):195–201

    Article  PubMed  Google Scholar 

  3. Roewer L. Y chromosome STR typing in crime casework. Forensic Sci Med Pathol, 2009,5(2):77–84

    Article  CAS  PubMed  Google Scholar 

  4. Haas C, Shved N, Rühli FJ, et al. Y-chromosomal analysis identifies the skeletal remains of Swiss national hero Jörg Jenatsch (1596–1639). Forensic Sci Int Genet, 2013,7(6):610–617

    Article  CAS  PubMed  Google Scholar 

  5. Ballantyne KN, Goedbloed M, Fang R, et al. Mutability of Y-chromosomal microsatellites: rates, characteristics, molecular bases, and forensic implications. Am J Hum Genet, 2010,87(3):341–353

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  6. Roewer L, Krawczak M, Willuweit S, et al. Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes. Forensic Sci Int, 2001,118(2):106–113

    Article  CAS  PubMed  Google Scholar 

  7. Hu SP. Genetic polymorphism of 12 Y-chromosomal STR loci in the Minnan Han Chinese in Southeast China. Forensic Sci Int, 2006,159(1):77–82

    Article  CAS  PubMed  Google Scholar 

  8. Hu SP, Wu DQ, Xu XH, et al. Genetic profile of 15 STR loci in the Min Nan population in Southeast China. Forensic Sci Int, 2005,152(2):263–265

    Article  CAS  PubMed  Google Scholar 

  9. Phillips CP, Syndercombe-Court D, Lareu MV, et al. Band shift analysis of three base-pair repeat alleles in the short tandem repeat locus D12S391. Forensic Sci Int, 1998,93(2):79–88

    Article  CAS  PubMed  Google Scholar 

  10. Crouse CA, Rogers S, Amiott E, et al. Analysis and interpretation of short tandem repeat microvariants and three-banded allele patterns using multiple allele detection systems. J Forensic Sci, 1999,44:87–94

    CAS  PubMed  Google Scholar 

  11. Nei M. Molecular evolutionary genetics. New York: Columbia University Press, 1987:180

    Google Scholar 

  12. Coble MD, Hill CR, Butler JM. Haplotype data for 23 Y-chromosome markers in four U.S. population groups. Forensic Sci Int Genet, 2013,7(3):e66–e68

    Article  CAS  PubMed  Google Scholar 

  13. Purps J, Siegert S, Willuweit S, et al. A global analysis of Y-chromosomal haplotype diversity for 23 STR loci. Forensic Sci Int Genet, 2014,12:12–23

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  14. Bär W, Brinkmann B, Budowle B, et al. DNA recommendations. Further report of the DNA Commission of the ISFH regarding the use of short tandem repeat systems. International Society for Forensic Haemogenetics. Int J Legal Med, 1997,110(4):175–176

    Google Scholar 

  15. Kovacevic L, Fatur-Ceric V, Hadzic N, et al. Haplotype data for 23 Y-chromosome markers in a reference sample from Bosnia and Herzegovina. Croat Med J, 2013,54(3):286–290

    Article  PubMed Central  PubMed  Google Scholar 

  16. Hu SP, Li H, Zhang FH, et al. Dominant contribution of northern Chinese to the paternal genetic structure of Chaoshanese in South China. Biochem Genet, 2011,49(7–8):483–498

    Article  CAS  PubMed  Google Scholar 

  17. Hammer MF, Chamberlain VF, Kearney VF, et al. Population structure of Y chromosome SNP haplogroups in the United States and forensic implications for constructing Y chromosome STR databases. Forensic Sci Int, 2006,164(1):45–55

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sheng-ping Hu  (胡盛平).

Additional information

This project was supported by grants from the Li Ka-Shing Foundation (Hong Kong, China), Cambridge University, UK (No. 432034), the Key Research Project of Shantou Science and Technology Bureau (No. 2005116), and the Shantou University Research and Development Fund (No. L00007).

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Shang, J., Hu, Sp. Haplotype data of 23 Y-chromosome markers in Minnan Han Chinese and comparison with those of 12 Y-chromosome markers. J. Huazhong Univ. Sci. Technol. [Med. Sci.] 35, 456–463 (2015). https://doi.org/10.1007/s11596-015-1453-y

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11596-015-1453-y

Key words

Navigation