References
Bjermo, H., Iggman, D., Kullberg, J., Dahlman, I., Johansson, L., Persson, L., Berglund, J., Pulkki, K., Basu, S., Uusitupa, M., Rudling, M., Arner, P., Cederholm, T., Ahlström, H., & Risérus, U. (2012). Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial. The American Journal of Clinical Nutrition, 95(5), 1003–1012.
Ramsden, C. E., Zamora, D., Majchrzak-Hong, S., et al. (2016). Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73). BMJ, 353, i1246.
Spector, A. A., & Kim, H. Y. (2015). Cytochrome P450 epoxygenase pathway of polyunsaturated fatty acid metabolism. Biochimica et Biophysica Acta, 1851(4), 356–365.
Edin, M. L., Hamedani, B. G., Gruzdev, A., Graves, J. P., Lih, F. B., Arbes III, S. J., Singh, R., Orjuela Leon, A. C., Bradbury, J. A., DeGraff, L. M., Hoopes, S. L., Arand, M., & Zeldin, D. C. (2018). Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia. The Journal of Biological Chemistry, 293(9), 3281–3292.
Panigrahy, D., Edin, M. L., Lee, C. R., Huang, S., Bielenberg, D. R., Butterfield, C. E., Barnés, C. M., Mammoto, A., Mammoto, T., Luria, A., Benny, O., Chaponis, D. M., Dudley, A. C., Greene, E. R., Vergilio, J. A., Pietramaggiori, G., Scherer-Pietramaggiori, S. S., Short, S. M., Seth, M., Lih, F. B., Tomer, K. B., Yang, J., Schwendener, R. A., Hammock, B. D., Falck, J. R., Manthati, V. L., Ingber, D. E., Kaipainen, A., D’Amore, P. A., Kieran, M. W., & Zeldin, D. C. (2012). Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. The Journal of Clinical Investigation, 122(1), 178–191.
Spiecker, M., Darius, H., Hankeln, T., Soufi, M., Sattler, A. M., Schaefer, J.̈. R., Node, K., Börgel, J., Mügge, A., Lindpaintner, K., Huesing, A., Maisch, B., Zeldin, D. C., & Liao, J. K. (2004). Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2. Circulation, 110(15), 2132–2136.
Wang, W., Sanidad, K. Z., & Zhang, G. (2019). Cytochrome P450 eicosanoid signaling pathway in colorectal tumorigenesis. Advances in Experimental Medicine and Biology, 1161, 115–123.
Hada, M., Edin, M. L., Hartge, P., Lih, F. B., Wentzensen, N., Zeldin, D. C., & Trabert, B. (2019). Prediagnostic serum levels of fatty acid metabolites and risk of ovarian cancer in the prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial. Cancer Epidemiology, Biomarkers & Prevention, 28(1), 189–197.
Wang, W., Yang, J., Edin, M. L., Wang, Y., Luo, Y., Wan, D., Yang, H., Song, C. Q., Xue, W., Sanidad, K. Z., Song, M., Bisbee, H. A., Bradbury, J. A., Nan, G., Zhang, J., Shih, P. A. B., Lee, K. S. S., Minter, L. M., Kim, D., Xiao, H., Liu, J. Y., Hammock, B. D., Zeldin, D. C., & Zhang, G. (2019). Targeted metabolomics identifies the cytochrome P450 monooxygenase eicosanoid pathway as a novel therapeutic target of colon tumorigenesis. Cancer Research, 79(8), 1822–1830.
Zhang, W., Li, H., Dong, H., Liao, J., Hammock, B. D., & Yang, G. Y. (2013). Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice. Anticancer Research, 33(12), 5261–5271.
Zhang, W., Yang, A. L., Liao, J., Li, H., Dong, H., Chung, Y. T., Bai, H., Matkowskyj, K. A., Hammock, B. D., & Yang, G. Y. (2012). Soluble epoxide hydrolase gene deficiency or inhibition attenuates chronic active inflammatory bowel disease in IL-10(-/-) mice. Digestive Diseases and Sciences, 57(10), 2580–2591.
Zhang, W., Liao, J., Li, H., Dong, H., Bai, H., Yang, A., Hammock, B. D., & Yang, G. Y. (2013). Reduction of inflammatory bowel disease-induced tumor development in IL-10 knockout mice with soluble epoxide hydrolase gene deficiency. Molecular Carcinogenesis, 52(9), 726–738.
Acknowledgments
This research is supported by USDA NIFA 2019-67017-29248 and NIH/NCI R03CA218520 (to G.Z.) and the Intramural Research Program of the NIH, National Institute of Environmental Health Sciences Z01 ES025034 (to D.C.Z.).
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Edin, M.L., Duval, C., Zhang, G. et al. Role of linoleic acid-derived oxylipins in cancer. Cancer Metastasis Rev 39, 581–582 (2020). https://doi.org/10.1007/s10555-020-09904-8
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DOI: https://doi.org/10.1007/s10555-020-09904-8