Abstract
Purpose
To evaluate the repeatability of corneal deformation parameters measured using a dynamic Scheimpflug analyzer and the impact of baseline clinical factors on the repeatability of each parameter.
Study design
Retrospective, cross-sectional study.
Methods
Forty-eight eyes (48 healthy subjects; mean age, 49.0 ± 19.5 years) underwent repeated examinations with the Scheimpflug analyzer to evaluate the test–retest variability. The intraclass correlation coefficient (ICC) and repeatability coefficient as indicators of variability were computed for 35 parameters measured with the Scheimpflug analyzer. The associations between the magnitude of the test–retest variability and baseline factors, such as age, axial length (AL), intraocular pressure (IOP), and central corneal thickness (CCT), were analyzed.
Results
The test–retest repeatability was excellent for 22 (62.9%) of 35 parameters (ICC ≥ 0.75), good for seven (20%), (ICC ≥ 0.6), fair for four (11.4%), (ICC ≥ 0.4), and poor for two (5.7%) parameters (ICC < 0.4). Age was associated positively with the magnitude of variability in 13 (37.1%) parameters; measurement variability was affected significantly by AL (5 parameters, 14.3%) and CCT (7 parameters, 20%) but, except for one parameter not by IOP.
Conclusion
Most parameters of the dynamic Scheimpflug analyzer showed favorable measurement reliability in healthy subjects. However, six parameters showed poor-to-fair repeatability. Age, AL, and CCT significantly affected the repeatability of several parameters. These results should be considered when clinicians use this device in clinical practice.
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Acknowledgements
This study was supported by Japanese Ministry of Education, Culture, Sports, Science and Technology.
Conflicts of interest
A. Miki, Consultant fees (NIDEK), Honoraria (Alcon, Kowa, Otsuka, Pfizer, Santen); N. Maeda, Grants (Topcon), Consultant fees (Alcon), Lecture fees (AMO, B + L, HOYA, Johnson & Johnson, Menicon, Otsuka, Pfizer, Santen, Senjyu, TOMEY); T. Asai, None; Y. Ikuno, Grants (TOMEY, Topcon), Consultant fees (Bayer, Novartis); K. Nishida, Grants (Alcon, AMO, Bayer, HOYA, Kowa, Menicon, MSD, Novartis, Otsuka, Pfizer, Rhoto, Santen, Senju, Topcon, Wakamoto), Lecture fees (Alcon, Bayer, Boehringer Ingelheim, Chuo Sangio, HOYA, Johnson & Johnson, Kowa, Novartis, Otsuka, Pfizer, Santen, SEED, Senju).
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Miki, A., Maeda, N., Asai, T. et al. Measurement repeatability of the dynamic Scheimpflug analyzer. Jpn J Ophthalmol 61, 433–440 (2017). https://doi.org/10.1007/s10384-017-0534-9
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DOI: https://doi.org/10.1007/s10384-017-0534-9