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Effect of transfusion therapy on intracranial stenosis in a child with sickle cell anaemia

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References

  1. Mazzucco S, Diomedi M, Qureshi A, Sainati L, Padayachee ST (2017) Transcranial Doppler screening for stroke risk in children with sickle cell disease: a systematic review. Int J Stroke 12:580–588. https://doi.org/10.1177/1747493017706189

    Article  PubMed  Google Scholar 

  2. DeBaun MR, Jordan LC, King AA, Schatz J, Vichinsky E, Fox CK, McKinstry RC, Telfer P, Kraut MA, Daraz L, Kirkham FJ, Murad MH (2020) American Society of Hematology 2020 guidelines for sickle cell disease: prevention, diagnosis, and treatment of cerebrovascular disease in children and adults. Blood Adv 4:1554–1588. https://doi.org/10.1182/bloodadvances.2019001142

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Adams RJ, McKie VC, Hsu L, Files B, Vichinsky E, Pegelow C, Abboud M, Gallagher D, Kutlar A, Nichols FT, Bonds DR, Brambilla D (1998) Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. N Engl J Med 339:5–11. https://doi.org/10.1056/NEJM199807023390102

    Article  CAS  PubMed  Google Scholar 

  4. Bishop S, Matheus MG, Abboud MR, Cane ID, Adams RJ, Jackson SM, Kalpatthi R (2011) Effect of chronic transfusion therapy on progression of neurovascular pathology in pediatric patients with sickle cell anemia. Blood Cells Mol Dis 47:125–128. https://doi.org/10.1016/j.bcmd.2011.06.002

    Article  PubMed  Google Scholar 

  5. https://www.haemoglobin.org.uk/wp-content/uploads/2020/03/tcdstandards.pdf, last accessed on 31/03/21

  6. Buchanan ID, James-Herry A, Osunkwo I (2013) The other side of abnormal: a case series of low transcranial Doppler velocities associated with stroke in children with sickle cell disease. J Pediatr Hematol Oncol 35:543–546

    Article  Google Scholar 

  7. Abboud MR, Cure J, Granger S, Gallagher D, Hsu L, Wang W, Woods G, Berman B, Brambilla D, Pegelow C, Lewin J, Zimmermann RA, Adams RJ (2004) Magnetic resonance angiography in children with sickle cell disease and the abnormal transcranial Doppler ultrasonography findings enrolled in the STOP study. Blood 103:2822–2826. https://doi.org/10.1182/blood-2003-06-1972

    Article  CAS  PubMed  Google Scholar 

  8. Bader-Meunier B, Verlhac S, Elmaleh-Bergès M et al (2008) Effect of transfusion therapy on cerebral vasculopathy in children with sickle-cell anemia. Haematologica 93:123–126

    Google Scholar 

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Acknowledgements

Dr Brunelli is supported by Campus Biomedico University of Rome PhD programme. Dr Mazzucco is supported by the National Institute for Health and Research (NIHR) Biomedical Research Centre, Oxford. We thank Dr Davide Simonato for his help with MRI image acquisition.

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Correspondence to Sara Mazzucco.

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Brunelli, N., Mohamed, B.P., Fuschi, M. et al. Effect of transfusion therapy on intracranial stenosis in a child with sickle cell anaemia. Neurol Sci 42, 3449–3451 (2021). https://doi.org/10.1007/s10072-021-05232-z

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  • DOI: https://doi.org/10.1007/s10072-021-05232-z

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