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Daily physical activity measured by a wearable activity monitoring device in patients with rheumatoid arthritis

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Abstract

Introduction

Activities of daily living in patients with rheumatoid arthritis (RA) have been evaluated by patient-reported outcomes. However, it has been difficult to measure activity intensity quantitively. Calories expended, exercise, and steps were measured quantitively by a wearable activity meter, and their associations with patients’ background characteristics were examined.

Methods

Data from a prospective, observational study (CHIKARA study) were used. Eighty-five of 100 RA patients were entered and wore a wearable activity meter for 7 days. The daily calories expended and exercise for both walking and housework and steps were evaluated. Total daily calories expended and exercise was defined as the sum of walking and housework. The relationships of DAS28-ESR, mHAQ, body composition, muscle function, and general status were analyzed.

Results

The median age was 66.0 years, and the disease duration was 5.3 years. DAS28-ESR was 3.11, and mHAQ was 0.125. Total daily calories expended, exercise, and number of steps were 461.7 kcal, 3.97 METs h, and 4,788, respectively. MHAQ, walking speed, power, locomotive syndrome, and frailty were independently related to exercise. Total daily exercise and steps of the moderate and high disease activity group were significantly lower than those of the remission group. When the number of steps was < 3,333 and < 2,468, the odds ratios for locomotive syndrome and frailty increased 14.4-fold and 8.7-fold, respectively, using Fisher’s exact test (P < 0.001).

Conclusions

Daily physical activity and number of steps were significantly decreased in RA patients with moderate and high disease activity as measured by a wearable activity meter.

Key Points

• Total daily calories expended and exercise for both walking and housework and steps in patients with rheumatoid arthritis were 461.7 kcal, 3.97 METs h, and 4,788, respectively, using a wearable activity meter.

• Daily physical activity, especially total daily exercise and number of steps, was significantly decreased in RA patients with moderate and high disease activity.

• When total daily steps were < 3,333 and < 2,468, the odds ratios for locomotive syndrome and frailty increased 14.4-fold and 8.7-fold, respectively.

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Acknowledgements

The authors are profoundly grateful for the cooperation of the patients with rheumatoid arthritis in the CHIKARA study.

Funding

This study was supported by a Grant-in-aid for Osteoporosis and Quality of Life 2015 from the Japan Osteoporosis Foundation.

Author information

Authors and Affiliations

  1. Department of Orthopaedic Surgery, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka, 534-0021, Japan

    Masahiro Tada & Noriaki Hidaka

  2. Department of Orthopaedic Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan

    Yutaro Yamada

  3. Department of Orthopaedic Surgery, Osaka Saiseikai Nakatsu Hospital, 2-10-39 Shibata, Kita-ku, Osaka, 530-0012, Japan

    Koji Mandai

  4. Search Institute for Bone and Arthritis Disease (SINBAD), Shirahama Foundation for Health and Welfare, 1447 Shirahama-cho, Nishimuro-gun, Wakayama, 649-2211, Japan

    Yoshinari Matsumoto

  5. Department of Medical Nutrition, Osaka City University Graduate School of Human Life Science, 3-3-138 Sugimoto-cho, Sumiyoshi-ku, Osaka, 558-8585, Japan

    Yoshinari Matsumoto

Authors
  1. Masahiro Tada
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Contributions

All authors were involved in drafting the article or revising it critically for important intellectual content, and all authors approved the final version to be submitted for publication. Dr. Tada had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Masahiro Tada: Study design, data collection, data analysis, drafting the manuscript.

Yutaro Yamada: Drafting the manuscript and data collection.

Koji Mandai: Drafting the manuscript and data analysis.

Yoshinari Matsumoto: Drafting the manuscript.

Noriaki Hidaka: Drafting the manuscript.

Corresponding author

Correspondence to Masahiro Tada.

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Ethics approval

The Ethics Committee of Osaka City General Hospital approved the study protocol. Written, informed consent was obtained from all patients and volunteers to participate in this study in accordance with the Declaration of Helsinki. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional committee (No. 1505018; July 7, 2015) and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. All patients provided written, informed consent prior to participation.

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Tada, M., Yamada, Y., Mandai, K. et al. Daily physical activity measured by a wearable activity monitoring device in patients with rheumatoid arthritis. Clin Rheumatol 41, 2011–2019 (2022). https://doi.org/10.1007/s10067-022-06147-6

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  • DOI: https://doi.org/10.1007/s10067-022-06147-6

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