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Refractory epileptic seizures due to vitamin B6 deficiency in a patient with Parkinson’s disease under duodopa® therapy

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Abstract

Levodopa/carbidopa intestinal gel (LCIG) infusion for the treatment of advanced Parkinson’s disease (PD) has been suspected to provoke polyneuropathy in conjunction with vitamin B6, B12 and folate deficiency and elevated homocysteine levels. We describe a PD patient under LCIG therapy developing refractory epileptic seizures obviously promoted by vitamin B6 deficiency.

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Authors and Affiliations

  1. Department of Neurology, Knappschaftskrankenhaus, Hospital of the Ruhr-University Bochum, Bochum, Germany

    Sabine Skodda

  2. Department of Neurology, St. Joseph Hospital Berlin-Weißensee, Berlin, Germany

    Thomas Müller

Authors
  1. Sabine Skodda
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  2. Thomas Müller
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Correspondence to Sabine Skodda.

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Skodda, S., Müller, T. Refractory epileptic seizures due to vitamin B6 deficiency in a patient with Parkinson’s disease under duodopa® therapy. J Neural Transm 120, 315–318 (2013). https://doi.org/10.1007/s00702-012-0856-1

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  • DOI: https://doi.org/10.1007/s00702-012-0856-1

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