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Surgical results of pancreatoduodenectomy in elderly patients

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Abstract

Purpose

To assess the safety and feasibility of pancreatoduodenectomy (PD) in elderly patients, we investigated the clinical characteristics of patients aged ≥75 years, who underwent this procedure at our hospital.

Methods

Between November 2005 and December 2010, 84 patients underwent PD at Tokushima University Hospital. We analyzed the clinicopathological data and outcomes after PD in patients aged ≥75 years compared with those in patients <75 years.

Results

The preoperative characteristics of the elderly group (n = 28) were similar to those of the younger group (n = 56). The hemoglobin and albumin levels were significantly lower in the elderly patients (P < 0.05), who also had a higher rate of preoperative pulmonary dysfunction (P < 0.05). The operation time and intraoperative blood loss did not differ significantly between the groups, but the incidence of pneumonia was higher in the elderly group (P < 0.05). The overall survival rate did not differ significantly between the groups.

Conclusion

Advanced age alone does not have an adverse effect on surgical outcomes, including postoperative complications and long-term prognosis. Therefore, PD may be justified for selected elderly patients.

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Abbreviations

BMI:

Body mass index

WBC:

White blood cell

Hb:

Hemoglobin

AST:

Aspartate aminotransferase

Alb:

Albumin

T-Bil:

Total bilirubin

Cre:

Creatinine

IPMN:

Intraductal papillary mucinous neoplasm

IPMC:

Intraductal papillary mucinous carcinoma

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Conflict of interest

Shinichiro Yamada and his co-authors have no conflict of interest in reporting this research.

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Authors and Affiliations

  1. Department of Surgery, The University of Tokushima, 3-18-15 Kuramoto-cho, Tokushima, Tokushima, 770-8503, Japan

    Shinichiro Yamada, Mitsuo Shimada, Tohru Utsunomiya, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Hiroki Mori, Mami Kanamoto, Jun Hanaoka, Shuichi Iwahashi & Yu Saitoh

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  1. Shinichiro Yamada
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  2. Mitsuo Shimada
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  3. Tohru Utsunomiya
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  4. Yuji Morine
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  5. Satoru Imura
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  6. Tetsuya Ikemoto
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  7. Hiroki Mori
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  8. Mami Kanamoto
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  9. Jun Hanaoka
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  10. Shuichi Iwahashi
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  11. Yu Saitoh
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Corresponding author

Correspondence to Mitsuo Shimada.

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Yamada, S., Shimada, M., Utsunomiya, T. et al. Surgical results of pancreatoduodenectomy in elderly patients. Surg Today 42, 857–862 (2012). https://doi.org/10.1007/s00595-012-0169-x

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  • DOI: https://doi.org/10.1007/s00595-012-0169-x

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