Abstract
The efficacy of 5-chloro-2-methylthio-6-(1-napthyloxy)-1H-benzimidazole was evaluated with three commercial fasciolicides in terms of the percentage of egg reduction in cattle. Fifty Swiss cows were selected for inclusion in the trial based on finding eggs of Fasciola hepatica in their feces. On day 0, they were blocked in five groups (G) of ten animals each according to fecal egg counts. G1 received compound alpha at 12 mg/kg p.o.; G2 triclabendazole at 12 mg/kg p.o.; G3.closantel at 3.5 mg/kg s.c.; G4 clorsulon at 2.0 mg/kg s.c. G5 animals served as untreated controls. Fecal analysis was performed on days 0, 7, 14, 21, 28, 60 and 90. Efficacy was measured on days 14 and 21. In addition, the extension and intensity effects were determined on day 60. The percentage efficacy for groups 1–4 was 98.1, 98.7, 98.2 and 97.9 on day 14 and 98.5, 97.9, 97.7 and 97.9 on day 21, respectively. No statistical differences were observed between treated groups.
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Acknowledgements
The authors thank Dr. Marco Antonio Hidalgo from rancho "Copalar" for the use of facilities. The study was partially supported by CONACYT, Mexico, Project no. 34942-B. These experiments comply with the current laws of Mexico.
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Taken in part from the PhD thesis of Yolanda Vera Montenegro
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Vera Montenegro, Y., Ibarra Velarde, F., Quiroz Romero, H. et al. Field trial on the efficacy of an experimental fasciolicide compared with some commercial compounds in naturally infected cattle. Parasitol Res 91, 1–4 (2003). https://doi.org/10.1007/s00436-003-0901-y
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DOI: https://doi.org/10.1007/s00436-003-0901-y