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Osteogenesis imperfecta und Glaukom

Eine Fallbeschreibung

Osteogenesis imperfecta and glaucoma

A case report

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Zusammenfassung

Osteogenesis imperfecta (OI) ist eine Erkrankung des Kollagenstoffwechsels. Neben Defekten in der Knochensynthese sind okuläre Manifestationen bekannt wie blaue Skleren, Myopie, Glaukom und Keratokonus. Wir berichten über einen Patienten mit OI, bei dem bei progredienter glaukomatöser Optikusatrophie unter medikamentöser Druckregulation eine Trabekulektomie an beiden Augen durchgeführt wurde. Ein Jahr postoperativ wurde ein Augeninnendruck von 7–11 mmHg gemessen. Dieser Fallbericht zeigt exemplarisch die Besonderheiten bei fistulierender Glaukomchirurgie bei Patienten mit OI.

Abstract

Osteogenesis imperfecta (OI) is a connective tissue metabolic disorder with autosomal inheritance. Ocular involvement includes blue sclera, myopia, glaucoma and keratoconus in addition to bone synthesis defects. We report the case of a male patient with OI who suffered from progressive visual field defects and advanced glaucomatous optic atrophy and underwent trabeculectomy on both eyes. Intraocular pressures (IOP) of 7–11 mmHg were measured 1 year postoperatively. This report illustrates peculiarities in the surgical therapy of open angle glaucoma in patients with OI as well as the options for complication management.

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Authors and Affiliations

  1. Augenklinik und Poliklinik, Universitätsmedizin Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland

    J. Rosbach, U. Vossmerbaeumer, G. Renieri, N. Pfeiffer &  H. Thieme

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  1. J. Rosbach
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  2. U. Vossmerbaeumer
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  3. G. Renieri
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  4. N. Pfeiffer
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  5. H. Thieme
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Correspondence to H. Thieme.

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Rosbach, J., Vossmerbaeumer, U., Renieri, G. et al. Osteogenesis imperfecta und Glaukom. Ophthalmologe 109, 479–482 (2012). https://doi.org/10.1007/s00347-011-2455-1

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  • DOI: https://doi.org/10.1007/s00347-011-2455-1

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