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Vaskuläre Tumoren der Milz

Vascular proliferations of the spleen

  • Schwerpunkt: Pathologie der Milz
  • Published:
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Zusammenfassung

Vaskuläre Tumoren der Milz spiegeln die Vielfältigkeit der Endothelformen in der Milz wider. So gibt es neben Hämangiomen auch milzspezifische Sinuswandzellangiome, die oft paraneoplastisch auftreten können und daher differenzialdiagnostisch gegenüber Metastasen abzugrenzen sind. Als maligner Tumor ist in erster Linie das Angiosarkom der Milz zu nennen. Als relativ neu beschriebene Entität wird die sklerosierende angiomatöse noduläre Transformation (SANT) vorgestellt, die häufig als Zufallsbefund bei bildgebenden Untersuchungen gefunden wird.

Abstract

Vascular proliferations of the spleen reflect the variability of vascular structures occurring in the normal spleen. Besides haemangiomas, there is a spleen-specific vascular neoplasm, littoral cell angioma, that often occurs as a paraneoplastic lesion and thus may require the differential diagnostic delineation of metastases to the spleen in patients with known neoplasms. The most common malignant vascular tumours of the spleen are angiosarcomas. A recently described vascular lesion of unknown pathogenesis, sclerosing angiomatoid nodular transformation (SANT) of the spleen, usually is an incidental finding detected in the course of imaging studies.

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Authors and Affiliations

  1. Institut für Pathologie, Städtisches Klinikum Karlsruhe, Moltkestraße 90, 76133, Karlsruhe, Deutschland

    M. Hartmann &  T. Rüdiger

  2. Institut für Pathologie, Universitätsklinikum Mannheim, Mannheim, Deutschland

    A. Marx

  3. Institut für Pathologie, Universität Würzburg, Würzburg, Deutschland

    E. Geißinger & H.K. Müller-Hermelink

Authors
  1. M. Hartmann
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  2. A. Marx
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  3. E. Geißinger
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  4. H.K. Müller-Hermelink
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  5. T. Rüdiger
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Correspondence to T. Rüdiger.

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Hartmann, M., Marx, A., Geißinger, E. et al. Vaskuläre Tumoren der Milz. Pathologe 29, 129–135 (2008). https://doi.org/10.1007/s00292-008-0971-9

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  • DOI: https://doi.org/10.1007/s00292-008-0971-9

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