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CT differentiation of 1–2-cm gallbladder polyps: benign vs malignant

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Abstract

Purpose

To evaluate MDCT findings of 1–2-cm sized gallbladder (GB) polyps for differentiation between benign and malignant polyps.

Methods

Institutional review board approval was obtained, and informed consent was waived. Portal venous phase CT scans of 1–2-cm sized GB polyps caused by various pathologic conditions were retrospectively reviewed by two blinded observers. Among the 36 patients identified, 21 had benign polyps with the remaining 15 having malignant polyps. Size, margin, and shape of GB polyps were evaluated. Attenuation values of the polyps, including mean attenuation, maximum attenuation, and standard deviation, were recorded. As determined by visual inspection, the degree of polyp enhancement was evaluated. Using these CT findings, each of the two radiologists assessed and recorded individual diagnostic confidence for differentiating benign versus malignant polyps on a 5-point scale. The diagnostic performance of CT was evaluated using a receiver operating characteristic curve analysis.

Results

There was no significant difference in size between benign and malignant GB polyps. Ill-defined margin and sessile morphology were significantly associated with malignant polyp. There was a significant difference in mean and maximum attenuation values between benign and malignant GB polyps. Mean standard deviation value of malignant polyps was significantly higher than that of benign polyps. All malignant polyps showed either hyperenhancement or marked hyperenhancement. A z value for the diagnosis of malignant GB polyps was 0.905.

Conclusion

Margin, shape, and enhancement degree are helpful in differentiating between benign and malignant polyps of 1–2-cm sizes.

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Authors and Affiliations

  1. Department of Diagnostic Radiology, Konyang University Hospital, Konyang University College of Medicine, 685 Gasuwon-dong, Seo-gu, Daejeon, 302-718, Republic of Korea

    E Rang Song, Woo-Suk Chung, Hye Young Jang & Minjae Yoon

  2. Department of Pathology, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Republic of Korea

    Eun Jung Cha

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  1. E Rang Song
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  2. Woo-Suk Chung
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  3. Hye Young Jang
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  4. Minjae Yoon
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Correspondence to Woo-Suk Chung.

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Song, E.R., Chung, WS., Jang, H.Y. et al. CT differentiation of 1–2-cm gallbladder polyps: benign vs malignant. Abdom Imaging 39, 334–341 (2014). https://doi.org/10.1007/s00261-013-0071-z

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  • DOI: https://doi.org/10.1007/s00261-013-0071-z

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