Skip to main content
SpringerLink
Log in

The outcome of urine culture positive and culture negative staghorn calculi after minimally invasive percutaneous nephrolithotomy

  • Original Paper
  • Published:
Urolithiasis Aims and scope Submit manuscript

Abstract

The purpose of this study was to compare the treatment outcomes of staghorn stones using minimally invasive percutaneous nephrolithotomy (MPCNL) in patients who had positive preoperative urine culture to patients with negative urine culture. The records of 284 patients with staghorn calculi, who underwent MPCNL in our center from January 2012 to January 2013, were retrospectively analyzed. Patients were divided into positive and negative group, according to the result of preoperative urine culture. Staghorn stones with negative culture received a single dose of broad spectrum antibiotic prophylaxis, whereas stones with positive culture were treated for at least 72 h according to antibiogram. The perioperative findings and postoperative outcomes were compared between the two groups. There were 70 (24.6 %) patients with positive and 214 (75.4 %) patients with negative preoperative urine culture who underwent MPCNL. There were no statistical differences in the duration of hospital stay, operative time, estimated blood loss, final stone free rate (SFR) as well as the incidence of the following infectious complications such as fever, systemic inflammatory response syndrome and septic shock, between both groups. Our retrospective study showed that MPCNL was a safe and effective modality in the treatment of staghorn stones. The morbidity, complication, and SFR were similar between patients with positive and negative preoperative urine cultures, once the culture positive infections were adequately controlled.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Abbreviations

MPCNL:

Minimally invasive percutaneous nephrolithotomy

PCNL:

Percutaneous nephrolithotomy

SIRS:

Systemic inflammatory response syndrome

SFR:

Stone free rate

CBC:

Routine complete blood count

SWL:

Shock wave lithotripsy

KUB:

Kidneys, ureters and bladder

CT:

Computed tomography

References

  1. Healy KA, Ogan K (2007) Pathophysiology and management of infectious staghorn calculi. Urol Clin North Am 34:363

    Article  PubMed  Google Scholar 

  2. Viprakasit DP, Sawyer MD, Herrell SD et al (2011) Changing composition of staghorn calculi. J Urol 186:2285

    Article  PubMed  Google Scholar 

  3. Soucy F, Ko R, Duvdevani M et al (2009) Percutaneous nephrolithotomy for staghorn calculi: a single center’s experience over 15 years. J Endourol 23:1669

    Article  PubMed  Google Scholar 

  4. Zhong W, Zeng G, Wu W et al (2011) Minimally invasive percutaneous nephrolithotomy with multiple mini tracts in a single session in treating staghorn calculi. Urol Res 39:117

    Article  PubMed  Google Scholar 

  5. Lojanapiwat B, Kitirattrakarn P (2011) Role of preoperative and intraoperative factors in mediating infection complication following percutaneous nephrolithotomy. Urol Int 86:448

    Article  CAS  PubMed  Google Scholar 

  6. El-Nahas AR, Eraky I, Shokeir AA et al (2012) Factors affecting stone-free rate and complications of percutaneous nephrolithotomy for treatment of staghorn stone. Urology 79:1236

    Article  PubMed  Google Scholar 

  7. Zeng G, Mai Z, Zhao Z et al (2013) Treatment of upper urinary calculi with Chinese minimally invasive percutaneous nephrolithotomy: a single-center experience with 12,482 consecutive patients over 20 years. Urolithiasis 41:225–229

    Google Scholar 

  8. Labate G, Modi P, Timoney A et al (2011) The percutaneous nephrolithotomy global study: classification of complications. J Endourol 25:1275

    Article  PubMed  Google Scholar 

  9. Wagenlehner FM, Pilatz A, Naber KG et al (2008) Therapeutic challenges of urosepsis. Eur J Clin Invest 38 Suppl 2:45

    Article  CAS  PubMed  Google Scholar 

  10. Mariappan P, Smith G, Bariol SV et al (2005) Stone and pelvic urine culture and sensitivity are better than bladder urine as predictors of urosepsis following percutaneous nephrolithotomy: a prospective clinical study. J Urol 173:1610

    Article  PubMed  Google Scholar 

  11. Dogan HS, Guliyev F, Cetinkaya YS et al (2007) Importance of microbiological evaluation in management of infectious complications following percutaneous nephrolithotomy. Int Urol Nephrol 39:737

    Article  PubMed  Google Scholar 

  12. Gutierrez J, Smith A, Geavlete P et al (2013) Urinary tract infections and post-operative fever in percutaneous nephrolithotomy. World J Urol 31:1135–1140

    Google Scholar 

  13. Liu C, Zhang X, Liu Y, Wang P (2013) Prevention and treatment of septic shock following mini-percutaneous nephrolithotomy: a single-center retrospective study of 834 cases. World J Urol 31:1593–1597

    Google Scholar 

  14. Keoghane SR, Cetti RJ, Rogers AE et al (2013) Blood transfusion, embolisation and nephrectomy after percutaneous nephrolithotomy (PCNL). BJU Int 111:628

    Article  PubMed  Google Scholar 

  15. Desai M, De Lisa A, Turna B et al (2011) The clinical research office of the endourological society percutaneous nephrolithotomy global study: staghorn versus nonstaghorn stones. J Endourol 25:1263

    Article  PubMed  Google Scholar 

  16. Matlaga BR, Hodges SJ, Shah OD et al (2004) Percutaneous nephrostolithotomy: predictors of length of stay. J Urol 172:1351

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.

Author information

Authors and Affiliations

  1. Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Kangda Road 1#, Haizhu District, Guangzhou, 510230, Guangdong, China

    Ming Lei, Wei Zhu, Shaw P. Wan, Yongda Liu, Guohua Zeng & Jian Yuan

  2. Guangdong Key Laboratory of Urology, Kangda Road 1#, Haizhu District, Guangzhou, 510230, Guangdong, China

    Ming Lei, Wei Zhu, Shaw P. Wan, Yongda Liu, Guohua Zeng & Jian Yuan

Authors
  1. Ming Lei
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wei Zhu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Shaw P. Wan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yongda Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Guohua Zeng
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jian Yuan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Guohua Zeng or Jian Yuan.

Additional information

M. Lei and W. Zhu contributed equally to this work as the co-first authors.

Jian Yuan and Guohua Zeng equally contributed to this work and should be considered as co-corresponding authors.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lei, M., Zhu, W., Wan, S.P. et al. The outcome of urine culture positive and culture negative staghorn calculi after minimally invasive percutaneous nephrolithotomy. Urolithiasis 42, 235–240 (2014). https://doi.org/10.1007/s00240-014-0645-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00240-014-0645-4

Keywords

Search

Navigation