Zusammenfassung
Die Arbeit beschreibt die neuesten Erkenntnisse über die Pathogenese des vorderen Knieschmerzes. Anhand eines „neuralen Modells“ wird die Entstehung des patellofemoralen Schmerzes erklärt. Gemäß verschiedener Studienresultaten wurde die Hypothese aufgestellt, dass wiederholt auftretende kurze Episoden einer Ischämie im lateralen Retinaculum durch das Auslösen einer neuralen Proliferation von nozizeptiven Axonen (Substanz-P-positive Nerven) mit hauptsächlich perivaskulärer Lokalisation einen vorderen Knieschmerz auslösen kann. Die Erkenntnisse stimmen dabei mit der Theorie der Homöostase überein, welche das Auftreten von patellofemoralen Schmerzen erklärt.
Abstract
We review the current status of knowledge in the field of pathogenesis of anterior knee pain in the young patient. Emphasis is placed on newer findings. We have developed what we call the “neural model” as an explanation for the genesis of anterior knee pain. According to our studies we hypothesize that periodic short episodes of ischemia in the lateral retinaculum could be implicated in the pathogenesis of anterior knee pain by triggering neural proliferation of nociceptive axons (substance P-positive nerves), mainly in a perivascular location. Our findings are compatible with the tissue homeostasis theory widely accepted currently to explain the genesis of anterior knee pain.
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Sanchis-Alfonso, V. Patellofemorale Schmerzen. Orthopäde 37, 835–840 (2008). https://doi.org/10.1007/s00132-008-1289-2
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DOI: https://doi.org/10.1007/s00132-008-1289-2