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Kindliche Nierentumoren — Relevanz der Bildgebung

Childhood kidney tumors — the relevance of imaging

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Zusammenfassung

6,2% der kindlichen Tumorerkrankungen betreffen die Nieren. Anamnese, Klinik und radiologischer Befund führen zur Differenzialdiagnose der verschiedenen Nierentumoren. Im Falle eines Nephroblastoms erfolgt die therapierelevante Diagnose allein radiologisch ohne histologische Sicherung. Im Rahmen der Therapieoptimierungsstudien der Gesellschaft für Pädiatrische Onkologie und Hämatologie wird eine präoperative Chemotherapie durchgeführt. Während und nach der präoperativen Chemotherapie erfolgt bildgebend ein Therapiemonitoring, um ein Ansprechen des Tumors auf die Therapie zu belegen. Das radiologische Staging hat große Bedeutung für die weitere Therapie und beeinflusst die Operationsplanung. Die präoperative Planung wird durch 3D-Visualisierung erleichtert. Die Relevanz der radiologischen Diagnostik von Nierentumoren im Kindesalter ergibt sich zusammenfassend aus Differenzialdiagnostik, Staging, Therapiemonitoring und Operationsplanung.

Abstract

Kidney tumors represent 6.2% of malignant tumors in children. History, clinical course and radiological findings are necessary elements in the differential diagnosis of the different renal tumors. In the case of nephroblastoma, chemotherapy is based solely on the radiological diagnosis without prior histology. In therapy-optimizing studies of the Society of Pediatric Oncology and Hematology, preoperative chemotherapy is performed. Therapy monitoring is performed in the course of and after preoperative chemotherapy to verify tumor response. Radiological staging plays a significant role in deciding on further treatment and in operative planning. Three-dimensional visualization of the abdominal situs can assist preoperative planning. In summary, diagnostic imaging in renal tumors in children plays a role in differential diagnosis, staging, monitoring of therapy, and surgical planning.

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Authors and Affiliations

  1. Abteilung Pädiatrische Radiologie, Universitätsklinik Heidelberg

    J.-P. Schenk, C. Schrader, S. Ley & J. Tröger

  2. Kinderchirurgie, Universitätsklinik Heidelberg

    P. Günther

  3. Klinik für Pädiatrische Hämatologie und Onkologie, Universitätsklinikum des Saarlandes, Homburg/Saar

    R. Furtwängler & N. Graf

  4. Institut für Paidopathologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel

    I. Leuschner

  5. Abteilung Pädiatrische Hämatologie und Onkologie, Universitätskinderklinik Heidelberg

    M. Edelhäuser

  6. Abteilung Pädiatrische Radiologie, Universitätsklinik Heidelberg, Im Neuenheimer Feld 153, 69120 , Heidelberg

    J.-P. Schenk

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  1. J.-P. Schenk
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Correspondence to J.-P. Schenk.

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Schenk, JP., Günther, P., Schrader, C. et al. Kindliche Nierentumoren — Relevanz der Bildgebung. Radiologe 45, 1112–1123 (2005). https://doi.org/10.1007/s00117-005-1260-8

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