Zusammenfassung
Osteonekrosen sind eine häufig beobachtete Nebenwirkung bei Patienten mit längerfristiger Cortison- oder Chemotherapie. Ein junger Patient mit einer akuten myeloischen Leukämie (AML) in Vollremission stellt sich mit Schulterschmerzen vor. Wegen einer Hüftkopfnekrose wurde dem Patienten bereits eine Hüft-TEP (-Totalendoprothese) implantiert. In der nachfolgenden Darstellung wird eine Therapiealternative zum Gelenkersatz bei Osteonekrosen am Humeruskopf im Rahmen eines Fallbeispieles vorgestellt.
Abstract
Osteonecrosis is a long known side effect in patients receiving cortisone or chemotherapy. A young patient was diagnosed with acute myeloid leukemia (AML) in 2005. After receiving combined cortisone and chemotherapy the patient was in complete remission. In 2007 a total hip replacement was necessary due to femoral head necrosis. Years after the joint replacement the patient reported acute shoulder pain without trauma. In this article an alternative procedure to an endoprothesis in a young patient with a humeral head osteonecrosis is presented.
Literatur
Wells L, Hosalkar HS, Crawford EA et al (2009) Thorough debridement under endoscopic visualization with bone grafting and stabilization for femoral head osteonecrosis in children. J Paediatr Orthop 29(4):319–326
Westhoff B, Jäger M, Krauspe R (2008) Osteonecrosis after Chemotherapy in children. Orthopade 37(1):56–62
Karimova EJ, Rai SN, Howard SC et al (2007) Femoral head osteonecrosis in pediatric and young adult patients with leukemia or lymphoma. J Clin Oncol 25(12):1525–1531
Prindull G, Weigel W et al (1982) Aseptic osteonecrosis in children treated for acute lymphoblastic leukemia and aplastic anemia. Eur J Pediatr 139(1):48–51
Dickschas J, Welsch G, Strecker W, Schöffl V (2011) Matrix-associated autologous chondrocyte transplantation combined with iliac crest bone graft for reconstruction of talus necrosis due to villonodular synovitis. J Foot Ankle Surg 51:87–90
Sawicka-Zukowska M, Kajdas L, Muszynska-Roslan K et al (2006) Avascular necrosis – an antineoplastic-treatment-related toxicity: the experiences of two institutions. Pediatr Hematol Oncol 23(8):625–629
Drescher W, Pufe T, Smeets R et al (2011) Avascular necrosis of the hip- diagnosis and treatment. Z Orthop Unfall 149(2):231–240
Elmantaser M, Stewart G, Young D et al (2010) Skeletal morbidity in children receiving chemotherapy for acute lymphoblastic leukemia. Arch Dis Child 95(10):805–809
Talamo G, Angtuaco E, Walker RC et al (2005) Avascular necorsis of femoral and/or humeral heads in multiple myeloma: results of a prospective study of patients treated with dexamethasone-based regimens and high-dose chemotherapy. J Clin Oncol 23(22):5217–5223
Brannon JK (2011) Thourough Debridement of the Humeral Head for Osteonecrosis. Orthopedics 34(1):56
Interessenkonflikt
Der korrespondierende Autor gibt für sich und seine Koautoren an, dass kein Interessenkonflikt besteht.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Heid, A., Dickschas, J. & Schoeffl, V. Cortison-induzierte Humeruskopfnekrose bei akuter myeloischer Leukämie. Unfallchirurg 116, 180–184 (2013). https://doi.org/10.1007/s00113-012-2243-7
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00113-012-2243-7